Interactor 1: LGR5 (O75473)
Leucine-rich repeat-containing G-protein coupled receptor 5 (G-protein coupled receptor 49) (G-protein coupled receptor 67) (G-protein coupled receptor HG38)
Gene: LGR5
Interactor 2: RSPO1 (Q2MKA7)
R-spondin-1 (Roof plate-specific spondin-1) (hRspo1)
Gene: RSPO1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.55 | 1.00 | 0.747 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23809763 |
| Identification Methods | x-ray crystallography, molecular sieving, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Furin-like_2~LRR_1, Furin-like_2~LRR_8 |
| Common GO terms | GO:0090263 - positive regulation of canonical Wnt signaling pathway |
| Homologous interactions | 8 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
