HitPredict

Interactor 1: RAB7 (O76742)
Ras-related protein Rab7 (DRab7) (EC 3.6.5.2) (Small monomeric GTPase Rab7) (Small ras-like GTPase)
Gene: RAB7

Interactor 2: Q9W293 (Q9W293)
Pleckstrin homology and RUN domain containing M1
Gene: Plekhm1

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	1.00	0.757

Property	Details
Experiments	25453831, 28483915
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Ras~zf-RING_9, RUN~Ras
Common GO terms	GO:0006906 - vesicle fusion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 207 Dm			1 720
+	Hs
		845558 RAB9A_HUMAN (1-207): 7.31e-83: 246: 47.83		PKHM3_HUMAN (384-709): 7.63e-118: 373: 37.58
+	Hs
		845017 RAB7A_HUMAN (1-207): 1.75e-81: 242: 76.33		PKHM3_HUMAN (384-709): 7.63e-118: 373: 37.58
+	Hs
		845645 RAB9A_HUMAN (1-207): 7.31e-83: 246: 47.83		RUBIC_HUMAN (421-711): 4.11e-110: 358: 27.12
+	Hs
		845013 RAB7A_HUMAN (1-207): 1.75e-81: 242: 76.33		DEFI8_HUMAN (450-708): 3.46e-107: 337: 31.18
+	Dm
		284090 RAB7_DROME (1-207): 2.04e-81: 242: 100.00		DEFI8_DROME (364-705): 2.56e-103: 326: 26.72
+	Hs
		845689 RAB9A_HUMAN (1-207): 7.31e-83: 246: 47.83		RUFY1_HUMAN (12-475): 8.52e-92: 302: 12.83
+	Hs
		1070359 RAB35_HUMAN (1-206): 2e-82: 245: 33.50		RUFY1_HUMAN (12-475): 8.52e-92: 302: 12.83
+	Hs
		914301 RB11A_HUMAN (3-206): 6e-82: 244: 28.30		RUFY1_HUMAN (12-475): 8.52e-92: 302: 12.83
+	Hs
		845561 RAB9A_HUMAN (1-207): 7.31e-83: 246: 47.83		RUFY3_HUMAN (20-402): 1.58e-84: 276: 15.75
+	Hs
		845020 RAB7A_HUMAN (1-207): 1.75e-81: 242: 76.33		RUFY3_HUMAN (20-402): 1.58e-84: 276: 15.75
+	Hs
		845637 RAB9A_HUMAN (1-207): 7.31e-83: 246: 47.83		RUFY2_HUMAN (12-474): 1.02e-79: 268: 13.48
+	Hs
		845697 RAB9A_HUMAN (1-207): 7.31e-83: 246: 47.83		FYCO1_HUMAN (21-467): 6.12e-69: 248: 16.34
+	Hs
		845629 RAB9A_HUMAN (1-207): 7.31e-83: 246: 47.83		SNX29_HUMAN (7-307): 5.95e-63: 226: 20.46
+	Hs
		1070318 RAB35_HUMAN (1-206): 2e-82: 245: 33.50		SNX29_HUMAN (7-307): 5.95e-63: 226: 20.46
+	Hs
		845102 RAB7A_HUMAN (1-207): 1.75e-81: 242: 76.33		SNX29_HUMAN (7-307): 5.95e-63: 226: 20.46
+	Hs
		1070261 RAB35_HUMAN (1-206): 2e-82: 245: 33.50		DEN5B_HUMAN (16-181): 2.84e-47: 183: 24.61
+	Hs
		914156 RB11A_HUMAN (3-206): 6e-82: 244: 28.30		DEN5B_HUMAN (16-181): 2.84e-47: 183: 24.61
+	Dm
		185562 RAB2_DROME (4-203): 1.1e-82: 246: 34.83		Q9VK31_DROME (7-303): 7.57e-45: 170: 19.18
+	Hs
		845587 RAB9A_HUMAN (1-207): 7.31e-83: 246: 47.83		PKHM2_HUMAN (16-504): 3.16e-41: 164: 16.80
+	Hs
		845059 RAB7A_HUMAN (1-207): 1.75e-81: 242: 76.33		PKHM2_HUMAN (16-504): 3.16e-41: 164: 16.80