HitPredict

Interactor 1: CLK1 (P49759)
Dual specificity protein kinase CLK1 (EC 2.7.12.1) (CDC-like kinase 1)
Gene: CLK1

Interactor 2: SRS12 (Q8WXF0)
Serine/arginine-rich splicing factor 12 (35 kDa SR repressor protein) (SRrp35) (Splicing factor, arginine/serine-rich 13B) (Splicing factor, arginine/serine-rich 19)
Gene: SRSF12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.555

Property	Details
Experiments	34133714
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 484 Hs			1 261
+	Hs
		284094 CLK1_HUMAN (1-484): 3.52e-162: 469: 100.00		SRS10_HUMAN (1-229): 6.38e-34: 125: 50.00
+	Hs
		889396 CLK1_HUMAN (1-484): 3.52e-162: 469: 100.00		SRSF3_HUMAN (1-92): 1.69e-23: 95: 32.61
+	Hs
		284233 CLK4_HUMAN (1-482): 2.32e-145: 426: 78.72		SRS10_HUMAN (1-229): 6.38e-34: 125: 50.00
+	Hs
		889625 CLK2_HUMAN (1-481): 5.01e-134: 398: 52.98		SRS12_HUMAN (1-261): 3.97e-38: 136: 100.00
+	Hs
		889428 CLK1_HUMAN (1-484): 3.52e-162: 469: 100.00		SRSF7_HUMAN (1-108): 2.54e-09: 58.2: 35.78
+	Hs
		284095 CLK2_HUMAN (1-481): 5.01e-134: 398: 52.98		SRS10_HUMAN (1-229): 6.38e-34: 125: 50.00
+	Hs
		889777 CLK3_HUMAN (1-480): 7.81e-126: 377: 48.35		SRS12_HUMAN (1-261): 3.97e-38: 136: 100.00
+	Hs
		889561 CLK2_HUMAN (1-481): 5.01e-134: 398: 52.98		ELAV2_HUMAN (3-92): 2.37e-26: 107: 23.91
+	Hs
		667816 CDK2_HUMAN (158-484): 7.76e-137: 397: 25.45		ELAV2_HUMAN (3-92): 2.37e-26: 107: 23.91
+	Hs
		284096 CLK3_HUMAN (1-480): 7.81e-126: 377: 48.35		SRS10_HUMAN (1-229): 6.38e-34: 125: 50.00
+	Hs
		889552 CLK2_HUMAN (1-481): 5.01e-134: 398: 52.98		SRSF3_HUMAN (1-92): 1.69e-23: 95: 32.61
+	Hs
		550181 CLK2_HUMAN (1-481): 5.01e-134: 398: 52.98		PABP1_HUMAN (2-101): 9.15e-20: 90.2: 17.00
+	Hs
		550125 CDK2_HUMAN (158-484): 7.76e-137: 397: 25.45		PABP1_HUMAN (2-101): 9.15e-20: 90.2: 17.00
+	Hs
		889720 CLK3_HUMAN (1-480): 7.81e-126: 377: 48.35		ELAV2_HUMAN (3-92): 2.37e-26: 107: 23.91
+	Hs
		889711 CLK3_HUMAN (1-480): 7.81e-126: 377: 48.35		SRSF3_HUMAN (1-92): 1.69e-23: 95: 32.61
+	Hs
		889723 CLK3_HUMAN (1-480): 7.81e-126: 377: 48.35		PABP4_HUMAN (2-101): 5.11e-21: 94.1: 18.00
+	Hs
		550182 CLK3_HUMAN (1-480): 7.81e-126: 377: 48.35		PABP1_HUMAN (2-101): 9.15e-20: 90.2: 17.00
+	Hs
		889574 CLK2_HUMAN (1-481): 5.01e-134: 398: 52.98		SRSF7_HUMAN (1-108): 2.54e-09: 58.2: 35.78
+	Hs
		667882 CDK2_HUMAN (158-484): 7.76e-137: 397: 25.45		SRSF7_HUMAN (1-108): 2.54e-09: 58.2: 35.78
+	Hs
		889743 CLK3_HUMAN (1-480): 7.81e-126: 377: 48.35		SRSF7_HUMAN (1-108): 2.54e-09: 58.2: 35.78