HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: EP400 (Q96L91)
E1A-binding protein p400 (EC 3.6.4.-) (CAG repeat protein 32) (Domino homolog) (hDomino) (Trinucleotide repeat-containing gene 12 protein) (p400 kDa SWI2/SNF2-related protein)
Gene: EP400

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Helicase_C~WD40, SNF2-rel_dom~WD40
Common GO terms	GO:0003682 - chromatin binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 441 Hs			1 3159
+	Hs
		1380090 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		EP400_HUMAN (1-3159): 0: 1359: 100.00
+	Hs
		1387495 SNR40_HUMAN (298-441): 2.31e-21: 96.6: 14.29		EP400_HUMAN (1-3159): 0: 1359: 100.00
+	Mm
		1244292 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		SMCA1_MOUSE (1512-2455): 0: 639: 14.20
+	Hs
		285095 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		SMCA1_HUMAN (1508-2455): 0: 637: 14.43
+	Mm
		1362466 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		SMCA5_MOUSE (1508-2466): 0: 635: 14.54
+	Hs
		243487 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		SMCA5_HUMAN (1508-2466): 0: 634: 14.44
+	Hs
		285283 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		CHD4_HUMAN (1499-2520): 2.75e-159: 548: 13.32
+	Mm
		1243972 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		CHD4_MOUSE (1499-2534): 1.83e-158: 546: 13.20
+	Hs
		160150 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		CHD2_HUMAN (1523-2416): 1.5e-158: 544: 13.94
+	Hs
		285150 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		SMCA2_HUMAN (1506-2307): 1.6e-136: 473: 14.77
+	Hs
		703359 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		SMCA1_HUMAN (1508-2455): 0: 637: 14.43
+	Hs
		703360 SNR40_HUMAN (298-441): 2.31e-21: 96.6: 14.29		SMCA1_HUMAN (1508-2455): 0: 637: 14.43
+	Hs
		1132879 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		CHD4_HUMAN (1499-2520): 2.75e-159: 548: 13.32
+	Mm
		1047380 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		SMRCD_MOUSE (1895-2042): 1.18e-24: 115: 40.54
+	Dm
		1472137 FBXW7_DROME (224-441): 2.91e-25: 111: 15.53		INO80_DROME (1887-2145): 3.22e-74: 278: 26.92
+	Mm
		59411 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		CHD7_MOUSE (2-478): 1.44e-11: 73.4: 10.92
+	Hs
		285151 EED_HUMAN (1-441): 1.63e-90: 283: 100.00		SMCA4_HUMAN (2530-2882): 2.27e-09: 65.7: 10.62
+	Mm
		1189468 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		SMCA4_MOUSE (2793-3115): 8.25e-09: 64.1: 9.54
+	Hs
		903450 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		SMCA4_HUMAN (2530-2882): 2.27e-09: 65.7: 10.62
+	Hs
		903453 SNR40_HUMAN (298-441): 2.31e-21: 96.6: 14.29		SMCA4_HUMAN (2530-2882): 2.27e-09: 65.7: 10.62