HitPredict

Interactor 1: STX11 (O75558)
Syntaxin-11
Gene: STX11

Interactor 2: VTI1A (Q96AJ9)
Vesicle transport through interaction with t-SNAREs homolog 1A (Vesicle transport v-SNARE protein Vti1-like 2) (Vti1-rp2)
Gene: VTI1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000149 - SNARE binding GO:0005484 - SNAP receptor activity GO:0005794 - Golgi apparatus GO:0006886 - intracellular protein transport GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 287 Hs			1 217
+	Hs
		160272 STX1A_HUMAN (1-286): 2.83e-70: 220: 28.67		GOSR2_HUMAN (5-212): 2.09e-53: 172: 14.09
+	Ce
		194914 STX1A_CAEEL (2-286): 5.02e-66: 209: 28.42		GOSR2_CAEEL (5-216): 8.57e-54: 173: 18.52
+	Dm
		1174552 STX1A_DROME (10-286): 7.21e-68: 214: 26.72		Q9W0N6_DROME (3-214): 2.02e-50: 165: 36.53
+	Dm
		1174545 STX1A_DROME (10-286): 7.21e-68: 214: 26.72		GOSR2_DROME (5-212): 3.59e-50: 164: 18.14
+	Hs
		1159653 STX1A_HUMAN (1-286): 2.83e-70: 220: 28.67		VTI1B_HUMAN (2-216): 3.27e-47: 157: 27.80
+	Mm
		313463 Q8BH40_MOUSE (56-286): 1.55e-50: 169: 14.96		VTI1A_MOUSE (1-217): 8.13e-66: 204: 94.93
+	Hs
		746226 STX2_HUMAN (1-286): 7.66e-68: 214: 31.82		VTI1B_HUMAN (2-216): 3.27e-47: 157: 27.80
+	Hs
		160910 STX16_HUMAN (13-276): 1.14e-49: 168: 16.17		VTI1A_HUMAN (1-217): 2.22e-63: 197: 100.00
+	Hs
		160261 STX4_HUMAN (1-286): 1.55e-58: 190: 27.53		GOSR2_HUMAN (5-212): 2.09e-53: 172: 14.09
+	Hs
		286734 STX11_HUMAN (1-287): 1.26e-63: 203: 100.00		VTI1B_HUMAN (2-216): 3.27e-47: 157: 27.80
+	At
		1456367 SYP43_ARATH (7-285): 1.33e-45: 158: 12.98		VTI12_ARATH (1-215): 8.95e-62: 193: 28.51
+	At
		265742 SYP41_ARATH (7-285): 2.05e-45: 157: 11.93		VTI12_ARATH (1-215): 8.95e-62: 193: 28.51
+	At
		1456368 SYP42_ARATH (10-286): 8.57e-45: 156: 14.29		VTI12_ARATH (1-215): 8.95e-62: 193: 28.51
+	Hs
		1087330 STX4_HUMAN (1-286): 1.55e-58: 190: 27.53		VTI1B_HUMAN (2-216): 3.27e-47: 157: 27.80
+	At
		1456369 SYP43_ARATH (7-285): 1.33e-45: 158: 12.98		VTI11_ARATH (1-216): 4.46e-60: 189: 32.13
+	At
		265743 SYP41_ARATH (7-285): 2.05e-45: 157: 11.93		VTI11_ARATH (1-216): 4.46e-60: 189: 32.13
+	Mm
		1296525 Q8BH40_MOUSE (56-286): 1.55e-50: 169: 14.96		Q91XH6_MOUSE (2-217): 4.07e-54: 174: 29.02
+	Mm
		267003 STX7_MOUSE (56-287): 2.23e-49: 166: 14.89		VTI1B_MOUSE (2-217): 4.12e-54: 174: 29.02
+	Hs
		1100732 STX3_HUMAN (1-276): 4.4e-55: 181: 30.44		VTI1B_HUMAN (2-216): 3.27e-47: 157: 27.80
+	Dm
		84849 STX1A_DROME (10-286): 7.21e-68: 214: 26.72		B7Z0M0_DROME (109-214): 1.84e-15: 71.7: 27.36