HitPredict

Interactor 1: UBP2 (O75604)
Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2)
Gene: USP2

Interactor 2: KRT34 (O76011)
Keratin, type I cuticular Ha4 (Hair keratin, type I Ha4) (Keratin-34) (K34)
Gene: KRT34

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.50	0.553

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 605 Hs			1 394
+	Hs
		288438 UBP2_HUMAN (1-605): 0: 634: 100.00		K1C40_HUMAN (4-387): 3.34e-144: 418: 63.68
+	Hs
		288346 UBP2_HUMAN (1-605): 0: 634: 100.00		K1C15_HUMAN (55-367): 4.99e-105: 319: 56.69
+	Hs
		288410 UBP2_HUMAN (1-605): 0: 634: 100.00		KT33B_HUMAN (1-394): 5.66e-95: 291: 88.83
+	Hs
		288480 UBP2_HUMAN (1-605): 0: 634: 100.00		KRT35_HUMAN (1-394): 8.06e-82: 259: 68.27
+	Hs
		288413 UBP2_HUMAN (1-605): 0: 634: 100.00		K1H1_HUMAN (1-393): 5.52e-79: 250: 88.80
+	Hs
		1230309 UBP21_HUMAN (72-604): 1.37e-127: 388: 35.15		K1C40_HUMAN (4-387): 3.34e-144: 418: 63.68
+	Hs
		566319 UBP36_HUMAN (162-598): 1.94e-101: 334: 26.70		K1C13_HUMAN (45-378): 2.42e-137: 401: 52.84
+	Hs
		828198 UBP8_HUMAN (159-602): 5.88e-125: 396: 34.00		KRT85_HUMAN (2-394): 1.84e-94: 293: 25.57
+	Hs
		1449295 UBP36_HUMAN (162-598): 1.94e-101: 334: 26.70		KRT84_HUMAN (17-384): 3.17e-103: 318: 26.83
+	Hs
		300554 UBP8_HUMAN (159-602): 5.88e-125: 396: 34.00		KRT36_HUMAN (3-374): 2.76e-78: 250: 71.62
+	Hs
		828213 UBP8_HUMAN (159-602): 5.88e-125: 396: 34.00		K1H1_HUMAN (1-393): 5.52e-79: 250: 88.80
+	Hs
		475637 UBP32_HUMAN (540-597): 1.12e-09: 63.9: 46.55		K1C19_HUMAN (48-368): 1.14e-137: 400: 54.21
+	Hs
		476417 UBP15_HUMAN (451-597): 1.61e-28: 123: 43.92		K1C16_HUMAN (54-381): 2.75e-107: 325: 56.71
+	Hs
		1127829 UBP15_HUMAN (451-597): 1.61e-28: 123: 43.92		KRT81_HUMAN (2-394): 2.5e-96: 298: 25.57
+	Hs
		300535 UBP15_HUMAN (451-597): 1.61e-28: 123: 43.92		KRT34_HUMAN (1-394): 1.57e-96: 295: 100.00
+	Hs
		1007553 UBP15_HUMAN (451-597): 1.61e-28: 123: 43.92		KRT85_HUMAN (2-394): 1.84e-94: 293: 25.57
+	Hs
		1127693 UBP15_HUMAN (451-597): 1.61e-28: 123: 43.92		KT33B_HUMAN (1-394): 5.66e-95: 291: 88.83
+	Hs
		90694 UBP15_HUMAN (451-597): 1.61e-28: 123: 43.92		C4AM86_HUMAN (2-394): 1.75e-93: 288: 67.99
+	Hs
		1367994 UBP15_HUMAN (451-597): 1.61e-28: 123: 43.92		KRT35_HUMAN (1-394): 8.06e-82: 259: 68.27
+	Hs
		1146223 UBP15_HUMAN (451-597): 1.61e-28: 123: 43.92		K1H1_HUMAN (1-393): 5.52e-79: 250: 88.80