Interactor 1: DNM3B (O88509)
DNA (cytosine-5)-methyltransferase 3B (Dnmt3b) (EC 2.1.1.37) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB)
Gene: Dnmt3b

Interactor 2: BMI1 (P25916)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4)
Gene: BMI1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 17726103
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000792 - heterochromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0006346 - DNA methylation-dependent heterochromatin formation
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 859
Mm

1 324
+ Mm

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Last updated: 15 Jul 2024