HitPredict

Interactor 1: NEMO (O88522)
NF-kappa-B essential modulator (NEMO) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: Ikbkg

Interactor 2: RIPK1 (Q60855)
Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)
Gene: RIPK1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.640

The method score is based on:

Property Details
Experiments 17981138, 22037414, 11479302
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0033209 - tumor necrosis factor-mediated signaling pathway
GO:0035591 - signaling adaptor activity
GO:0042803 - protein homodimerization activity
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0044877 - protein-containing complex binding
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 412
Mm

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Last updated: 15 Jul 2024