Interactor 1: BECN1 (O88597)
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]
Gene: BECN1

Interactor 2: PRKN (Q9WVS6)
E3 ubiquitin-protein ligase parkin (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase)
Gene: PRKN

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 23737459, 24879156
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000423 - mitophagy
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0010506 - regulation of autophagy
and 3 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 448
Mm

1 464
+ Rn
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024