Interactor 1: SLIT2 (O94813)
Slit homolog 2 protein (Slit-2) [Cleaved into: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product]
Gene: SLIT2
Interactor 2: ROBO1 (Q9Y6N7)
Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1)
Gene: ROBO1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.47 | 1.00 | 0.692 |
The method score is based on:
Property | Details |
---|---|
Experiments | 17848514 |
Identification Methods | surface plasmon resonance, x-ray crystallography |
Interaction Type | direct interaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Ig_3~Laminin_G_1, I-set~LRR_8, Ig_3~LRR_8 |
Common GO terms | GO:0002042 - cell migration involved in sprouting angiogenesis GO:0003180 - aortic valve morphogenesis GO:0003184 - pulmonary valve morphogenesis GO:0005737 - cytoplasm GO:0021836 - chemorepulsion involved in postnatal olfactory bulb interneuron migration and 5 others more... |
Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024