HitPredict

Interactor 1: AGRL1 (O94910)
Adhesion G protein-coupled receptor L1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1) (Latrophilin-1) (Lectomedin-2)
Gene: ADGRL1

Interactor 2: CLC2D (Q9UHP7)
C-type lectin domain family 2 member D (Lectin-like NK cell receptor) (Lectin-like transcript 1) (LLT-1) (Osteoclast inhibitory lectin)
Gene: CLEC2D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007166 - cell surface receptor signaling pathway GO:0016020 - membrane GO:0030246 - carbohydrate binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1474 Hs			1 191
+	Hs
		1334796 AGRL3_HUMAN (8-1474): 0: 1428: 52.01		CLC2D_HUMAN (1-191): 2.05e-63: 196: 100.00
+	Hs
		426872 AGRL3_HUMAN (8-1474): 0: 1428: 52.01		ASGR2_HUMAN (23-189): 1.21e-46: 156: 21.08
+	Hs
		823112 AGRE5_HUMAN (399-1137): 1.01e-155: 495: 25.16		CLC2D_HUMAN (1-191): 2.05e-63: 196: 100.00
+	Hs
		1218780 AGRA3_HUMAN (359-1390): 1.55e-130: 439: 15.76		CLC4A_HUMAN (42-191): 3.17e-38: 133: 18.79
+	Hs
		1218776 AGRA3_HUMAN (359-1390): 1.55e-130: 439: 15.76		CLC2B_HUMAN (48-187): 3.95e-37: 127: 41.43
+	Hs
		1133829 AGRF1_HUMAN (500-1169): 2.3e-101: 348: 18.99		CLC2D_HUMAN (1-191): 2.05e-63: 196: 100.00
+	Hs
		1028498 AGRG6_HUMAN (483-1131): 7.22e-116: 396: 22.70		KLRD1_HUMAN (33-189): 2.76e-34: 121: 24.72
+	Hs
		1357156 AGRG1_HUMAN (544-1105): 5.17e-100: 338: 19.33		CLC4E_HUMAN (12-186): 2.39e-41: 140: 22.77
+	Hs
		1166146 OLFM4_HUMAN (161-394): 3.24e-28: 122: 35.77		CL17A_HUMAN (72-187): 1.27e-40: 142: 31.20
+	Hs
		1166170 OLFM4_HUMAN (161-394): 3.24e-28: 122: 35.77		CLC7A_HUMAN (20-187): 5.72e-36: 127: 20.00