HitPredict

Interactor 1: KRT38 (O76015)
Keratin, type I cuticular Ha8 (Hair keratin, type I Ha8) (Keratin-38) (K38)
Gene: KRT38

Interactor 2: FYCO1 (Q9BQS8)
FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7)
Gene: FYCO1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 456 Hs			1 1478
+	Hs
		227259 KRT86_HUMAN (9-454): 1.25e-95: 298: 25.00		FYCO1_HUMAN (1-1478): 1.9e-144: 482: 100.00
+	Hs
		300358 KRT34_HUMAN (58-447): 4.8e-156: 449: 60.77		PLEC_HUMAN (385-1169): 2.59e-09: 64.7: 22.38
+	Hs
		385111 K1C14_HUMAN (102-415): 3.24e-147: 429: 52.87		PLEC_HUMAN (385-1169): 2.59e-09: 64.7: 22.38
+	Hs
		772754 K1C17_HUMAN (100-415): 5.87e-99: 305: 52.85		MYH9_HUMAN (574-1367): 8.52e-33: 141: 12.76
+	Hs
		49879 A1A4E9_HUMAN (93-424): 1.7e-95: 296: 50.74		MYH1_HUMAN (574-1355): 1.07e-29: 131: 12.06
+	Hs
		556836 K1C13_HUMAN (93-424): 1.86e-95: 296: 50.74		MYH1_HUMAN (574-1355): 1.07e-29: 131: 12.06
+	Hs
		67555 K1C39_HUMAN (92-454): 1.43e-110: 337: 57.22		MYH7B_HUMAN (660-1330): 3.37e-15: 83.7: 12.26
+	Hs
		563058 K1C40_HUMAN (1-432): 3.89e-87: 274: 49.89		MYH8_HUMAN (574-1355): 1.3e-30: 134: 11.80
+	Hs
		556936 K1C40_HUMAN (1-432): 3.89e-87: 274: 49.89		MYH7_HUMAN (7-712): 2.71e-30: 133: 10.32
+	Hs
		300758 KRT38_HUMAN (1-456): 4.52e-88: 277: 100.00		EEA1_HUMAN (1-727): 2.37e-29: 129: 12.52
+	Hs
		556859 K1C40_HUMAN (1-432): 3.89e-87: 274: 49.89		MYH1_HUMAN (574-1355): 1.07e-29: 131: 12.06
+	Hs
		1141688 K1C40_HUMAN (1-432): 3.89e-87: 274: 49.89		EEA1_HUMAN (1-727): 2.37e-29: 129: 12.52
+	Hs
		1143158 K1C39_HUMAN (92-454): 1.43e-110: 337: 57.22		PLEC_HUMAN (385-1169): 2.59e-09: 64.7: 22.38
+	Hs
		535943 K1C40_HUMAN (1-432): 3.89e-87: 274: 49.89		MYH3_HUMAN (617-1366): 3.99e-27: 123: 11.82
+	Hs
		773163 K1C17_HUMAN (100-415): 5.87e-99: 305: 52.85		MYH10_HUMAN (5-484): 1.16e-17: 91.8: 9.50
+	Hs
		475512 K1C19_HUMAN (100-412): 8.69e-100: 306: 50.48		DESP_HUMAN (232-1121): 6.85e-14: 79.7: 22.05
+	Hs
		587630 K1C17_HUMAN (100-415): 5.87e-99: 305: 52.85		DESP_HUMAN (232-1121): 6.85e-14: 79.7: 22.05
+	Hs
		475580 K1C19_HUMAN (100-412): 8.69e-100: 306: 50.48		PLEC_HUMAN (385-1169): 2.59e-09: 64.7: 22.38
+	Hs
		227225 KRT86_HUMAN (9-454): 1.25e-95: 298: 25.00		PLEC_HUMAN (385-1169): 2.59e-09: 64.7: 22.38
+	Hs
		476319 K1C16_HUMAN (100-421): 9.58e-95: 295: 51.55		PLEC_HUMAN (385-1169): 2.59e-09: 64.7: 22.38