HitPredict

Interactor 1: NEBL (O76041)
Nebulette (Actin-binding Z-disk protein)
Gene: NEBL

Interactor 2: ZO1 (Q07157)
Tight junction protein 1 (Tight junction protein ZO-1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: TJP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH3_2~SH3_9
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1014 Hs			1 1748
+	Hs
		1058829 SPTN1_HUMAN (359-1013): 3.75e-39: 161: 11.50		ZO1_HUMAN (1-1748): 0: 924: 100.00
+	Mm
		811946 SRC8_MOUSE (523-1012): 1.78e-39: 156: 13.28		ZO1_MOUSE (1-1748): 0: 871: 90.85
+	Hs
		1058852 SH319_HUMAN (954-1013): 1.62e-16: 86.6: 41.67		ZO1_HUMAN (1-1748): 0: 924: 100.00
+	Hs
		1058831 SRC8_HUMAN (284-641): 3.72e-12: 72.1: 14.37		ZO1_HUMAN (1-1748): 0: 924: 100.00
+	Hs
		302212 NEBL_HUMAN (1-1014): 0: 665: 100.00		ZO2_HUMAN (391-609): 2.16e-09: 64.9: 18.62
+	Dm
		1471537 Q9VDF4_DROME (501-1013): 2.04e-39: 156: 14.13		Q9VHK4_DROME (14-1358): 2.26e-170: 556: 26.73
+	Dm
		355644 O96046_DROME (501-1013): 5.7e-41: 161: 14.50		Q7K4E2_DROME (14-817): 8.64e-173: 551: 35.04
+	Mm
		1223178 PACN1_MOUSE (634-1013): 4.63e-42: 162: 14.88		DLG4_MOUSE (1-112): 1.44e-26: 120: 29.92
+	Mm
		597654 SPTN1_MOUSE (359-1013): 5.52e-39: 160: 11.65		DLG4_MOUSE (1-112): 1.44e-26: 120: 29.92
+	Mm
		1223548 SH3G2_MOUSE (646-1013): 2.48e-33: 134: 14.63		DLG4_MOUSE (1-112): 1.44e-26: 120: 29.92
+	Mm
		1223547 SRBS1_MOUSE (913-1013): 1.22e-11: 71.2: 30.39		DLG4_MOUSE (1-112): 1.44e-26: 120: 29.92
+	Hs
		250297 VINEX_HUMAN (858-1010): 1.08e-13: 77.3: 27.45		DLG5_HUMAN (262-508): 3.84e-17: 90.3: 21.43
+	Hs
		1124664 SRC8_HUMAN (284-641): 3.72e-12: 72.1: 14.37		DLG5_HUMAN (262-508): 3.84e-17: 90.3: 21.43
+	Hs
		1133187 LASP1_HUMAN (496-672): 7.52e-19: 89.4: 25.14		ZO2_HUMAN (391-609): 2.16e-09: 64.9: 18.62
+	Hs
		1205171 SH319_HUMAN (954-1013): 1.62e-16: 86.6: 41.67		ZO2_HUMAN (391-609): 2.16e-09: 64.9: 18.62
+	Hs
		1416516 SRBS1_HUMAN (881-1013): 1.5e-10: 67.7: 24.81		ZO2_HUMAN (391-609): 2.16e-09: 64.9: 18.62