HitPredict

Interactor 1: CIAO1 (O76071)
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39)
Gene: CIAO1

Interactor 2: SEC12 (Q9HCU5)
Guanine nucleotide-exchange factor SEC12 (Prolactin regulatory element-binding protein)
Gene: PREB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 339 Hs			1 417
+	Hs
		302801 CIAO1_HUMAN (1-337): 3.88e-105: 313: 100.00		WDR5_HUMAN (29-269): 2.87e-37: 139: 9.27
+	Hs
		302772 CIAO1_HUMAN (1-337): 3.88e-105: 313: 100.00		LIS1_HUMAN (251-411): 1.1e-30: 123: 12.43
+	Hs
		1334151 POC1B_HUMAN (92-339): 5.35e-60: 201: 20.97		POC1A_HUMAN (142-407): 2.46e-60: 203: 15.64
+	Dm
		1463899 WDS_DROME (137-339): 6.23e-48: 166: 20.69		WDS_DROME (9-331): 4.5e-59: 198: 9.76
+	Hs
		921980 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		COPA_HUMAN (11-310): 1.72e-37: 146: 12.35
+	Hs
		965141 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		WDR5_HUMAN (29-269): 2.87e-37: 139: 9.27
+	Hs
		992873 POC1B_HUMAN (92-339): 5.35e-60: 201: 20.97		RACK1_HUMAN (160-364): 7.81e-19: 88.4: 16.02
+	Hs
		984306 GBB2_HUMAN (77-339): 2.99e-44: 156: 16.98		NLE1_HUMAN (224-391): 8.39e-34: 133: 11.91
+	Sp
		1068482 TUP11_SCHPO (175-339): 1.15e-29: 120: 15.76		TUP11_SCHPO (179-411): 3.51e-43: 161: 12.92
+	Hs
		992900 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		RACK1_HUMAN (160-364): 7.81e-19: 88.4: 16.02
+	Sp
		1068486 TUP11_SCHPO (175-339): 1.15e-29: 120: 15.76		TUP12_SCHPO (16-226): 1.03e-37: 146: 15.93
+	Hs
		1180240 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		SMU1_HUMAN (81-222): 4.53e-11: 66.6: 10.14
+	Hs
		965071 WDR5B_HUMAN (2-132): 1.34e-25: 106: 22.06		WDR5_HUMAN (29-269): 2.87e-37: 139: 9.27
+	Hs
		984066 GBB2_HUMAN (77-339): 2.99e-44: 156: 16.98		RACK1_HUMAN (160-364): 7.81e-19: 88.4: 16.02
+	Hs
		938199 SEC13_HUMAN (28-281): 8.1e-19: 87.4: 29.64		WDR5_HUMAN (29-269): 2.87e-37: 139: 9.27
+	Hs
		965276 NLE1_HUMAN (226-339): 2.41e-18: 87.4: 14.91		WDR5_HUMAN (29-269): 2.87e-37: 139: 9.27
+	Hs
		1450936 NLE1_HUMAN (226-339): 2.41e-18: 87.4: 14.91		NLE1_HUMAN (224-391): 8.39e-34: 133: 11.91
+	Sc
		793908 TAF5_YEAST (124-339): 2.23e-35: 138: 19.48		TAF5_YEAST (11-215): 2.1e-12: 71: 8.33
+	Ca
		515422 TUP1_CANAL (180-338): 2.08e-28: 116: 18.87		TUP1_CANAL (137-394): 1.32e-15: 80.7: 17.15
+	Hs
		992995 NLE1_HUMAN (226-339): 2.41e-18: 87.4: 14.91		RACK1_HUMAN (160-364): 7.81e-19: 88.4: 16.02