HitPredict

Interactor 1: CIAO1 (O76071)
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39)
Gene: CIAO1

Interactor 2: TBL2 (Q9Y4P3)
Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein)
Gene: TBL2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 339 Hs			1 447
+	Hs
		302772 CIAO1_HUMAN (1-337): 3.88e-105: 313: 100.00		LIS1_HUMAN (3-218): 1.16e-50: 178: 11.86
+	Hs
		302801 CIAO1_HUMAN (1-337): 3.88e-105: 313: 100.00		WDR5_HUMAN (4-165): 9.61e-31: 122: 8.93
+	Hs
		261440 TBL1R_HUMAN (3-283): 2.29e-63: 211: 25.52		TBL1X_HUMAN (3-310): 1.79e-53: 189: 14.15
+	Hs
		302717 CIAO1_HUMAN (1-337): 3.88e-105: 313: 100.00		CIAO1_HUMAN (81-215): 3.82e-16: 81.1: 18.12
+	Hs
		1334151 POC1B_HUMAN (92-339): 5.35e-60: 201: 20.97		POC1A_HUMAN (223-446): 3.65e-54: 187: 15.56
+	Hs
		1410246 TBL1R_HUMAN (3-283): 2.29e-63: 211: 25.52		TBL1Y_HUMAN (3-258): 7.32e-44: 162: 14.33
+	Dm
		1463899 WDS_DROME (137-339): 6.23e-48: 166: 20.69		WDS_DROME (222-447): 3.23e-52: 181: 16.74
+	Hs
		965141 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		WDR5_HUMAN (4-165): 9.61e-31: 122: 8.93
+	Hs
		992873 POC1B_HUMAN (92-339): 5.35e-60: 201: 20.97		RACK1_HUMAN (266-445): 5.7e-20: 91.9: 16.30
+	Hs
		992900 FBXW7_HUMAN (89-339): 8.41e-51: 181: 18.65		RACK1_HUMAN (266-445): 5.7e-20: 91.9: 16.30
+	Sp
		1068482 TUP11_SCHPO (175-339): 1.15e-29: 120: 15.76		TUP11_SCHPO (1-167): 4.09e-35: 139: 8.38
+	Hs
		984066 GBB2_HUMAN (77-339): 2.99e-44: 156: 16.98		RACK1_HUMAN (266-445): 5.7e-20: 91.9: 16.30
+	Hs
		984306 GBB2_HUMAN (77-339): 2.99e-44: 156: 16.98		NLE1_HUMAN (356-445): 3.96e-18: 88.3: 15.56
+	Hs
		302804 GBB2_HUMAN (77-339): 2.99e-44: 156: 16.98		CIAO1_HUMAN (81-215): 3.82e-16: 81.1: 18.12
+	Ca
		515422 TUP1_CANAL (180-338): 2.08e-28: 116: 18.87		TUP1_CANAL (327-446): 8.66e-27: 114: 10.53
+	Hs
		965071 WDR5B_HUMAN (2-132): 1.34e-25: 106: 22.06		WDR5_HUMAN (4-165): 9.61e-31: 122: 8.93
+	Hs
		965276 NLE1_HUMAN (226-339): 2.41e-18: 87.4: 14.91		WDR5_HUMAN (4-165): 9.61e-31: 122: 8.93
+	Sc
		793908 TAF5_YEAST (124-339): 2.23e-35: 138: 19.48		TAF5_YEAST (269-419): 6.94e-11: 66.4: 17.61
+	Sp
		1068486 TUP11_SCHPO (175-339): 1.15e-29: 120: 15.76		TUP12_SCHPO (5-121): 1.29e-15: 81: 13.95
+	Hs
		992995 NLE1_HUMAN (226-339): 2.41e-18: 87.4: 14.91		RACK1_HUMAN (266-445): 5.7e-20: 91.9: 16.30