HitPredict

Interactor 1: O76216 (O76216)
histone acetyltransferase (EC 2.3.1.48)
Gene: Gcn5

Interactor 2: TAD2A (Q7KSD8)
Transcriptional adapter 2A (dADA2a)
Gene: Ada2a

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.836

Property	Details
Experiments	12482983, 20813260, 38944040
Identification Methods	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, two hybrid, molecular sieving
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	Acetyltransf_1~Myb_DNA-binding
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0140672 - ATAC complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 813 Dm			1 562
+	Dm
		1269026 Q9VTZ1_DROME (1-813): 0: 1142: 99.63		TAD2A_DROME (1-562): 0: 668: 100.00
+	Mm
		1298677 KAT2B_MOUSE (35-813): 0: 1068: 44.82		TAD2A_MOUSE (81-557): 5.31e-143: 422: 31.41
+	Hs
		283520 KAT2B_HUMAN (71-813): 0: 1030: 47.01		TAD2A_HUMAN (81-557): 7.71e-146: 429: 30.99
+	Dm
		1302193 Q9VTZ1_DROME (1-813): 0: 1142: 99.63		TAD2B_DROME (92-441): 2.85e-96: 305: 24.52
+	Dm
		303749 O76216_DROME (1-813): 0: 1140: 100.00		TAD2B_DROME (92-441): 2.85e-96: 305: 24.52
+	Mm
		1298678 KAT2A_MOUSE (61-813): 0: 1021: 47.14		TAD2A_MOUSE (81-557): 5.31e-143: 422: 31.41
+	Hs
		283519 KAT2A_HUMAN (58-813): 0: 1013: 47.10		TAD2A_HUMAN (81-557): 7.71e-146: 429: 30.99
+	Hs
		1287314 KAT2B_HUMAN (71-813): 0: 1030: 47.01		TAD2B_HUMAN (89-560): 1.22e-136: 405: 23.57
+	Hs
		1287313 KAT2A_HUMAN (58-813): 0: 1013: 47.10		TAD2B_HUMAN (89-560): 1.22e-136: 405: 23.57
+	Sc
		1036333 GCN5_YEAST (398-811): 1.14e-165: 488: 37.44		ADA2_YEAST (91-555): 1.57e-137: 407: 21.78
+	At
		1409037 GCN5_ARATH (453-806): 2.8e-149: 451: 41.76		TAD2A_ARATH (91-553): 1.63e-127: 386: 20.23
+	At
		1409029 GCN5_ARATH (453-806): 2.8e-149: 451: 41.76		TAD2B_ARATH (73-553): 4.61e-128: 385: 21.77
+	Sc
		850562 GCN5_YEAST (398-811): 1.14e-165: 488: 37.44		RSC8_YEAST (42-343): 5.88e-52: 188: 12.95
+	Pf
		1301960 Q8IB67_PLAF7 (435-808): 2.48e-137: 444: 38.42		Q8I5G5_PLAF7 (58-209): 8.76e-29: 123: 13.77
+	At
		1373506 GTE11_ARATH (623-810): 7.01e-39: 155: 21.33		SWI3C_ARATH (74-437): 7.75e-44: 168: 12.73
+	Sc
		777070 BDF1_YEAST (640-812): 2.08e-22: 104: 20.57		RSC8_YEAST (42-343): 5.88e-52: 188: 12.95
+	At
		1283655 GTE11_ARATH (623-810): 7.01e-39: 155: 21.33		SWI3B_ARATH (76-411): 4.27e-30: 125: 12.36
+	At
		1355409 GTE11_ARATH (623-810): 7.01e-39: 155: 21.33		SWI3A_ARATH (95-387): 2.18e-12: 71.5: 13.77