HitPredict

Interactor 1: O77434 (O77434)
EG:34F3.8 protein (LD45288p) (Secretory 22, isoform A)
Gene: Sec22

Interactor 2: SNAP (Q23983)
Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide-sensitive factor attachment protein)
Gene: alphaSnap

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	SNAP~Synaptobrevin
Common GO terms	GO:0016020 - membrane GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 211 Dm			1 292
+	Dm
		121790 M9PGI6_DROME (1-211): 4.13e-80: 239: 99.06		SNAP_DROME (1-292): 3.39e-109: 320: 100.00
+	Hs
		280163 SC22B_HUMAN (1-211): 2.08e-82: 245: 56.74		SNAA_HUMAN (17-290): 2.9e-106: 312: 61.68
+	Dm
		1171606 Q7JYX5_DROME (25-211): 6.12e-60: 188: 24.87		SNAP_DROME (1-292): 3.39e-109: 320: 100.00
+	Zm
		31396 A0A1D6KH00_MAIZE (25-211): 5.91e-66: 215: 19.90		A0A1D6PZ82_MAIZE (1-270): 7.63e-93: 280: 36.16
+	Hs
		907987 VAMP7_HUMAN (31-198): 7.9e-58: 183: 26.47		SNAA_HUMAN (17-290): 2.9e-106: 312: 61.68
+	Hs
		192222 YKT6_HUMAN (31-186): 2.32e-47: 155: 21.38		SNAA_HUMAN (17-290): 2.9e-106: 312: 61.68
+	Sc
		646219 SEC22_YEAST (1-211): 3.32e-64: 199: 30.37		SEC17_YEAST (6-290): 1.29e-86: 262: 31.94
+	Hs
		280315 SC22B_HUMAN (1-211): 2.08e-82: 245: 56.74		SNAG_HUMAN (7-249): 4.08e-67: 213: 19.92
+	Dm
		1171638 Q9W3M8_DROME (32-186): 7.68e-40: 136: 20.76		SNAP_DROME (1-292): 3.39e-109: 320: 100.00
+	Dm
		305578 O77434_DROME (1-211): 1.02e-81: 243: 100.00		Q9U6R9_DROME (4-263): 7.97e-58: 189: 19.01
+	Dm
		121810 M9PGI6_DROME (1-211): 4.13e-80: 239: 99.06		Q9U6R9_DROME (4-263): 7.97e-58: 189: 19.01
+	Dm
		121816 M9PGI6_DROME (1-211): 4.13e-80: 239: 99.06		Q9VH25_DROME (16-263): 7.6e-56: 183: 18.73
+	Sc
		743450 YKT6_YEAST (28-186): 1.9e-40: 138: 24.55		SEC17_YEAST (6-290): 1.29e-86: 262: 31.94
+	Hs
		116706 I1VE18_HUMAN (63-115): 1.36e-21: 85.4: 52.83		SNAA_HUMAN (17-290): 2.9e-106: 312: 61.68
+	Hs
		908047 VAMP7_HUMAN (31-198): 7.9e-58: 183: 26.47		SNAG_HUMAN (7-249): 4.08e-67: 213: 19.92
+	Dm
		1263454 Q7JYX5_DROME (25-211): 6.12e-60: 188: 24.87		Q9U6R9_DROME (4-263): 7.97e-58: 189: 19.01
+	Dm
		1263460 Q7JYX5_DROME (25-211): 6.12e-60: 188: 24.87		Q9VH25_DROME (16-263): 7.6e-56: 183: 18.73
+	Hs
		192305 YKT6_HUMAN (31-186): 2.32e-47: 155: 21.38		SNAG_HUMAN (7-249): 4.08e-67: 213: 19.92
+	Dm
		1458096 Q9W3M8_DROME (32-186): 7.68e-40: 136: 20.76		Q9U6R9_DROME (4-263): 7.97e-58: 189: 19.01
+	Dm
		1475482 Q9W3M8_DROME (32-186): 7.68e-40: 136: 20.76		Q9VH25_DROME (16-263): 7.6e-56: 183: 18.73