HitPredict

Interactor 1: VAMP5 (O95183)
Vesicle-associated membrane protein 5 (VAMP-5) (Myobrevin)
Gene: VAMP5

Interactor 2: BET1L (Q9NYM9)
BET1-like protein (Golgi SNARE with a size of 15 kDa) (GOS-15) (GS15) (Vesicle transport protein GOS15)
Gene: BET1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	30833792, 33961781
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 116 Hs			1 111
+	Hs
		169343 VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00		BET1_HUMAN (2-106): 3.67e-36: 120: 31.43
+	Hs
		169416 VAMP7_HUMAN (4-96): 5.88e-26: 98: 31.18		BET1_HUMAN (2-106): 3.67e-36: 120: 31.43
+	Hs
		169594 VAMP8_HUMAN (2-74): 9.04e-26: 94.2: 26.03		BET1_HUMAN (2-106): 3.67e-36: 120: 31.43
+	Hs
		235133 VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00		STX10_HUMAN (7-91): 6.07e-25: 95.9: 12.94
+	Hs
		169333 SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65		BET1_HUMAN (2-106): 3.67e-36: 120: 31.43
+	Hs
		169474 VAMP3_HUMAN (2-72): 2.01e-24: 90.7: 38.03		BET1_HUMAN (2-106): 3.67e-36: 120: 31.43
+	Hs
		263378 SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65		BET1L_HUMAN (1-111): 7.13e-35: 117: 100.00
+	Dm
		1178137 Q7JYX5_DROME (4-96): 1.36e-32: 114: 31.18		Q9VVX6_DROME (29-106): 1.21e-24: 91.6: 30.77
+	Dm
		577224 SYB_DROME (2-88): 9.74e-30: 105: 39.08		Q7JRF1_DROME (7-106): 9.37e-26: 99.7: 15.00
+	Hs
		212700 VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00		STX6_HUMAN (2-91): 2.24e-21: 86.6: 15.56
+	Dm
		577258 SYB_DROME (2-88): 9.74e-30: 105: 39.08		Q9VVX6_DROME (29-106): 1.21e-24: 91.6: 30.77
+	Hs
		235129 VAMP4_HUMAN (3-73): 1.13e-25: 95.3: 29.58		STX10_HUMAN (7-91): 6.07e-25: 95.9: 12.94
+	Rn
		1144363 VAMP1_RAT (2-78): 9.26e-27: 97.3: 37.66		STX6_RAT (1-92): 1.14e-22: 90.1: 16.30
+	Hs
		235130 SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65		STX10_HUMAN (7-91): 6.07e-25: 95.9: 12.94
+	Hs
		212772 VAMP7_HUMAN (4-96): 5.88e-26: 98: 31.18		STX6_HUMAN (2-91): 2.24e-21: 86.6: 15.56
+	Rn
		1144365 VAMP8_RAT (2-69): 7.27e-25: 91.9: 27.94		STX6_RAT (1-92): 1.14e-22: 90.1: 16.30
+	Hs
		212689 VAMP4_HUMAN (3-73): 1.13e-25: 95.3: 29.58		STX6_HUMAN (2-91): 2.24e-21: 86.6: 15.56
+	Hs
		212988 VAMP8_HUMAN (2-74): 9.04e-26: 94.2: 26.03		STX6_HUMAN (2-91): 2.24e-21: 86.6: 15.56
+	Hs
		212790 VAMP2_HUMAN (2-75): 2.33e-25: 93.8: 39.19		STX6_HUMAN (2-91): 2.24e-21: 86.6: 15.56
+	Hs
		212690 SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65		STX6_HUMAN (2-91): 2.24e-21: 86.6: 15.56