Interactor 1: O77430 (O77430)
GEO01111p1 (HL01263p) (RH26825p) (SKP1-related A, isoform A) (SKP1-related A, isoform B) (SKP1-related A, isoform C) (SKP1-related A, isoform E) (SKP1-related A, isoform F) (SKP1-related A, isoform G) (SKPA)
Gene: SkpA

Interactor 2: FBXW7 (Q9VZF4)
F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) (Protein archipelago)
Gene: ago

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.840

The method score is based on:

Property Details
Experiments 14605208, 15575970, 38944040
Identification Methods two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains F-box-like~Skp1, Skp1~WD40
Common GO terms GO:0005634 - nucleus
GO:0016567 - protein ubiquitination
GO:0019005 - SCF ubiquitin ligase complex
GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0042023 - DNA endoreduplication
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 162
Dm

1 1326
+ Sc
+ Mm
+ Hs
+ Hs
+ Mm
+ Xl
+ Ce
+ Sp
+ Sp
+ Sp
+ Hs
+ Mm
+ Dm
+ Dm
+ Hs
+ Mm
+ Dm
+ Sp
+ Dm
+ Sc

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Last updated: 11Aug2025