HitPredict

Interactor 1: SKI3 (O94474)
Superkiller protein 3
Gene: SKI3

Interactor 2: REC14 (Q09150)
Meiotic recombination protein rec14
Gene: REC14

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	26771498
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	TPR_19~WD40
Common GO terms	GO:0005829 - cytosol GO:0055087 - Ski complex GO:0070478 - nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay GO:0070481 - nuclear-transcribed mRNA catabolic process, non-stop decay
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1389 Sp			1 302
+	Hs
		718532 CDC27_HUMAN (522-917): 2.52e-34: 144: 13.38		WDR5_HUMAN (90-302): 6.18e-73: 229: 22.69
+	Hs
		185575 OGT1_HUMAN (1080-1388): 7.13e-25: 114: 10.94		WDR5_HUMAN (90-302): 6.18e-73: 229: 22.69
+	Hs
		1243857 CTR9_HUMAN (362-1105): 2.23e-32: 139: 10.53		SKI8_HUMAN (45-300): 4.58e-51: 172: 22.52
+	Mm
		1223457 CTR9_MOUSE (362-1105): 5.89e-32: 137: 10.53		SKI8_MOUSE (45-300): 1.66e-51: 173: 22.52
+	Hs
		194540 KDM6A_HUMAN (1054-1388): 4.18e-13: 76.7: 11.01		WDR5_HUMAN (90-302): 6.18e-73: 229: 22.69
+	Hs
		158690 UTY_HUMAN (105-514): 1.48e-12: 74.8: 11.22		WDR5_HUMAN (90-302): 6.18e-73: 229: 22.69
+	Hs
		104294 F5H5V6_HUMAN (444-714): 8.36e-11: 69.1: 15.55		WDR5_HUMAN (90-302): 6.18e-73: 229: 22.69
+	Hs
		1244373 SKI3_HUMAN (8-993): 9.79e-26: 117: 9.81		SKI8_HUMAN (45-300): 4.58e-51: 172: 22.52
+	Hs
		1387547 CRNL1_HUMAN (793-1334): 2.83e-18: 93.3: 10.63		SNR40_HUMAN (137-302): 2.44e-45: 158: 21.18
+	Hs
		731535 STIP1_HUMAN (7-525): 9.33e-10: 65.1: 12.09		SNR40_HUMAN (137-302): 2.44e-45: 158: 21.18
+	Hs
		185995 OGT1_HUMAN (1080-1388): 7.13e-25: 114: 10.94		TBL1R_HUMAN (182-302): 7.7e-23: 100: 24.82
+	Ca
		515424 Q5ADP3_CANAL (6-470): 6.61e-16: 85.5: 11.54		TUP1_CANAL (180-302): 3.43e-31: 123: 23.02
+	Hs
		194598 KDM6A_HUMAN (1054-1388): 4.18e-13: 76.7: 11.01		FBXW7_HUMAN (172-302): 5.84e-32: 126: 15.91
+	Hs
		1380295 TF3C3_HUMAN (3-747): 5.1e-12: 72.8: 9.82		FBXW7_HUMAN (172-302): 5.84e-32: 126: 15.91
+	Dm
		1264419 Q7K0X3_DROME (4-662): 5.2e-12: 73.1: 11.79		Q9XZ19_DROME (158-302): 2.74e-29: 115: 24.50
+	Sp
		238287 CYC8_SCHPO (35-422): 1.58e-17: 90.9: 9.57		TUP11_SCHPO (3-89): 1.11e-18: 88.1: 17.98
+	Sp
		238288 CYC8_SCHPO (35-422): 1.58e-17: 90.9: 9.57		TUP12_SCHPO (1-90): 5.05e-18: 86.2: 20.65
+	Hs
		209205 STIP1_HUMAN (7-525): 9.33e-10: 65.1: 12.09		PRP4_HUMAN (173-302): 2.57e-25: 106: 25.00
+	At
		81831 VIP6_ARATH (4-599): 4.01e-11: 70.1: 10.42		VIP3_ARATH (12-283): 5.41e-24: 101: 25.26
+	Hs
		731348 STIP1_HUMAN (7-525): 9.33e-10: 65.1: 12.09		SMU1_HUMAN (112-266): 3.49e-15: 77.4: 27.44