HitPredict

Interactor 1: SC24A (O95486)
Protein transport protein Sec24A (SEC24-related protein A)
Gene: SEC24A

Interactor 2: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1093 Hs			1 1114
+	Hs
		315631 SC24B_HUMAN (2-1093): 0: 796: 54.78		RET_HUMAN (1-1114): 0: 1295: 100.00
+	Hs
		315512 SC24A_HUMAN (1-1093): 0: 899: 100.00		FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61
+	Hs
		315518 SC24A_HUMAN (1-1093): 0: 899: 100.00		FGFR3_HUMAN (501-1061): 4.63e-147: 462: 33.16
+	Hs
		315499 SC24A_HUMAN (1-1093): 0: 899: 100.00		EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24
+	Hs
		315501 SC24A_HUMAN (1-1093): 0: 899: 100.00		ERBB2_HUMAN (428-1113): 6.03e-140: 456: 24.93
+	Hs
		315502 SC24A_HUMAN (1-1093): 0: 899: 100.00		NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69
+	Hs
		169156 SC24A_HUMAN (1-1093): 0: 899: 100.00		MUSK_HUMAN (396-1018): 1.21e-135: 434: 25.28
+	Hs
		315517 SC24A_HUMAN (1-1093): 0: 899: 100.00		FGFR4_HUMAN (535-1054): 4.33e-124: 401: 37.89
+	Hs
		315649 SC24B_HUMAN (2-1093): 0: 796: 54.78		FGFR2_HUMAN (501-1065): 3.92e-155: 484: 33.11
+	Hs
		315638 SC24B_HUMAN (2-1093): 0: 796: 54.78		FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61
+	Hs
		315652 SC24B_HUMAN (2-1093): 0: 796: 54.78		FGFR3_HUMAN (501-1061): 4.63e-147: 462: 33.16
+	Hs
		315564 SC24A_HUMAN (1-1093): 0: 899: 100.00		NTRK3_HUMAN (638-1020): 2.11e-106: 355: 31.19
+	Hs
		315620 SC24B_HUMAN (2-1093): 0: 796: 54.78		EGFR_HUMAN (428-1113): 5.86e-141: 457: 23.24
+	Hs
		315624 SC24B_HUMAN (2-1093): 0: 796: 54.78		ERBB2_HUMAN (428-1113): 6.03e-140: 456: 24.93
+	Hs
		315625 SC24B_HUMAN (2-1093): 0: 796: 54.78		NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69
+	Hs
		169157 SC24B_HUMAN (2-1093): 0: 796: 54.78		MUSK_HUMAN (396-1018): 1.21e-135: 434: 25.28
+	Hs
		315651 SC24B_HUMAN (2-1093): 0: 796: 54.78		FGFR4_HUMAN (535-1054): 4.33e-124: 401: 37.89
+	Hs
		315527 SC24A_HUMAN (1-1093): 0: 899: 100.00		VGFR3_HUMAN (677-1012): 1.84e-76: 278: 41.25
+	Hs
		315707 SC24B_HUMAN (2-1093): 0: 796: 54.78		NTRK3_HUMAN (638-1020): 2.11e-106: 355: 31.19
+	Hs
		315662 SC24B_HUMAN (2-1093): 0: 796: 54.78		VGFR3_HUMAN (677-1012): 1.84e-76: 278: 41.25