HitPredict

Interactor 1: CBX6 (O95503)
Chromobox protein homolog 6
Gene: CBX6

Interactor 2: GZF1 (Q9H116)
GDNF-inducible zinc finger protein 1 (Zinc finger and BTB domain-containing protein 23) (Zinc finger protein 336)
Gene: GZF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Hs			1 711
+	Hs
		316190 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		ZN624_HUMAN (37-709): 0: 712: 20.13
+	Hs
		316196 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		ZN107_HUMAN (191-710): 0: 570: 24.81
+	Hs
		64135 CBX5_HUMAN (11-106): 3.1e-28: 111: 29.17		ZN729_HUMAN (63-709): 0: 619: 23.21
+	Hs
		316192 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		ZN629_HUMAN (119-648): 1.15e-104: 341: 15.78
+	Hs
		64158 CBX5_HUMAN (11-106): 3.1e-28: 111: 29.17		ZN726_HUMAN (191-709): 0: 569: 25.43
+	Hs
		316135 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		ZN184_HUMAN (544-710): 1.18e-62: 224: 21.14
+	Hs
		1294636 MPP8_HUMAN (6-339): 4.19e-48: 177: 14.91		ZN845_HUMAN (373-710): 2.82e-121: 387: 28.90
+	Hs
		316039 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		ZKSC8_HUMAN (367-604): 6.78e-60: 213: 43.70
+	Hs
		315965 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		ZNF7_HUMAN (464-654): 3.45e-53: 197: 28.93
+	Hs
		316020 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		ZN33A_HUMAN (372-667): 4.24e-33: 138: 18.94
+	Hs
		316021 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		ZN33B_HUMAN (413-709): 1.97e-30: 130: 13.77
+	Hs
		800355 CBX5_HUMAN (11-106): 3.1e-28: 111: 29.17		ZN543_HUMAN (403-657): 7.75e-104: 331: 35.94
+	Hs
		316188 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		ZKSC7_HUMAN (102-257): 5.55e-10: 64.6: 9.62
+	Hs
		1316054 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		ZN717_HUMAN (93-228): 2.69e-26: 117: 11.03
+	Hs
		87558 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		C9JVC3_HUMAN (93-228): 9.22e-26: 115: 11.03
+	Hs
		203785 SUV91_HUMAN (11-222): 8.35e-36: 137: 17.21		ZN436_HUMAN (416-604): 2.24e-49: 181: 46.03
+	Hs
		123275 CBX4_HUMAN (1-362): 3.71e-34: 135: 23.28		ZN546_HUMAN (92-255): 3.13e-32: 135: 8.54
+	Hs
		67855 CBX5_HUMAN (11-106): 3.1e-28: 111: 29.17		ZN724_HUMAN (119-346): 1.48e-38: 153: 12.99
+	Hs
		123331 CBX4_HUMAN (1-362): 3.71e-34: 135: 23.28		ZKSC7_HUMAN (102-257): 5.55e-10: 64.6: 9.62
+	Hs
		800350 CBX5_HUMAN (11-106): 3.1e-28: 111: 29.17		ZNF45_HUMAN (636-710): 8e-10: 64: 5.13