Interactor 1: MK01 (P63085)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: Mapk1

Interactor 2: MK01 (P63085)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: Mapk1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.690

The method score is based on:

Property Details
Experiments 26267534
Identification Methods anti tag coimmunoprecipitation, blue native page, chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000165 - MAPK cascade
GO:0001784 - phosphotyrosine residue binding
GO:0003690 - double-stranded DNA binding
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
and 95 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 358
Mm

1 358
+ Hs
+ Rn
+ Hs
+ Hs
+ Rn
+ Hs
+ At
+ Dm
+ Zm
+ At
+ At
+ Hs
+ At
+ Kl
+ At
+ Hs
+ Hs

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Last updated: 15 Jul 2024