Interactor 1: RPA1 (O95602)
DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (A190) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (RPA194)
Gene: POLR1A

Interactor 2: RPA49 (Q9GZS1)
DNA-directed RNA polymerase I subunit RPA49 (RNA polymerase I subunit A49) (DNA-directed RNA polymerase I subunit E) (RNA polymerase I-associated factor 1) (RNA polymerase I-associated factor 53)
Gene: POLR1E

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 15226435, 34079125, 35271311, 26496610, 24207024, 24981860, 36271492, 19214185
Identification Methods far western blotting, proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation, chromatography technology
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_I_A49~RNA_pol_Rpb1_1
Common GO terms GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0005736 - RNA polymerase I complex
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1720
Hs

1 419
+ Sc
+ Hs
+ Hs

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Last updated: 15 Jul 2024