HitPredict

Interactor 1: RHBT1 (O94844)
Rho-related BTB domain-containing protein 1
Gene: RHOBTB1

Interactor 2: GNAI2 (P04899)
Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein)
Gene: GNAI2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37575477
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005886 - plasma membrane GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 696 Hs			1 355
+	Hs
		318715 RHBT1_HUMAN (1-696): 0: 538: 100.00		GNAS2_HUMAN (1-355): 7.36e-145: 417: 38.83
+	Hs
		418644 RAC1_HUMAN (12-219): 3.84e-73: 236: 35.55		GNAI2_HUMAN (1-355): 8.82e-180: 503: 100.00
+	Hs
		716009 CDC42_HUMAN (12-218): 1.56e-89: 279: 37.14		GNA11_HUMAN (1-354): 4.9e-162: 459: 50.42
+	Hs
		418639 RB11A_HUMAN (5-250): 4.16e-72: 234: 17.67		GNAI2_HUMAN (1-355): 8.82e-180: 503: 100.00
+	Hs
		418637 RHOA_HUMAN (16-215): 2.03e-68: 224: 36.45		GNAI2_HUMAN (1-355): 8.82e-180: 503: 100.00
+	Hs
		601182 RHOQ_HUMAN (10-213): 9.09e-84: 264: 37.68		GNA11_HUMAN (1-354): 4.9e-162: 459: 50.42
+	Hs
		482598 RB11A_HUMAN (5-250): 4.16e-72: 234: 17.67		GNAO_HUMAN (1-355): 1.32e-173: 488: 69.30
+	Hs
		955039 CDC42_HUMAN (12-218): 1.56e-89: 279: 37.14		GNAS2_HUMAN (1-355): 7.36e-145: 417: 38.83
+	Hs
		716016 RAC1_HUMAN (12-219): 3.84e-73: 236: 35.55		GNA11_HUMAN (1-354): 4.9e-162: 459: 50.42
+	Hs
		716013 RB11A_HUMAN (5-250): 4.16e-72: 234: 17.67		GNA11_HUMAN (1-354): 4.9e-162: 459: 50.42
+	Hs
		716008 RAC3_HUMAN (12-208): 1.37e-70: 229: 39.50		GNA11_HUMAN (1-354): 4.9e-162: 459: 50.42
+	Hs
		349314 RB11A_HUMAN (5-250): 4.16e-72: 234: 17.67		GNA14_HUMAN (3-354): 2.11e-158: 449: 49.86
+	Hs
		716012 RHOA_HUMAN (16-215): 2.03e-68: 224: 36.45		GNA11_HUMAN (1-354): 4.9e-162: 459: 50.42
+	Hs
		601231 RHOQ_HUMAN (10-213): 9.09e-84: 264: 37.68		GNAS2_HUMAN (1-355): 7.36e-145: 417: 38.83
+	Hs
		953446 RAC3_HUMAN (12-208): 1.37e-70: 229: 39.50		GNA13_HUMAN (2-354): 6.74e-153: 436: 39.72
+	Hs
		227489 SPOP_HUMAN (300-648): 4.67e-73: 242: 15.32		GNAS2_HUMAN (1-355): 7.36e-145: 417: 38.83
+	Hs
		988257 RAC1_HUMAN (12-219): 3.84e-73: 236: 35.55		GNAS2_HUMAN (1-355): 7.36e-145: 417: 38.83
+	Hs
		953383 RAC3_HUMAN (12-208): 1.37e-70: 229: 39.50		GNAS2_HUMAN (1-355): 7.36e-145: 417: 38.83
+	Hs
		989716 RHOG_HUMAN (12-210): 1.95e-69: 226: 36.63		GNAS2_HUMAN (1-355): 7.36e-145: 417: 38.83
+	Hs
		961935 RHOA_HUMAN (16-215): 2.03e-68: 224: 36.45		GNAS2_HUMAN (1-355): 7.36e-145: 417: 38.83