HitPredict

Interactor 1: BRD1 (O95696)
Bromodomain-containing protein 1 (BR140-like protein) (Bromodomain and PHD finger-containing protein 2)
Gene: BRD1

Interactor 2: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0030425 - dendrite
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1058 Hs			1 2115
+	Hs
		876692 BRPF1_HUMAN (2-1058): 0: 834: 50.04		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		319112 BRD1_HUMAN (1-1058): 0: 1027: 100.00		MYH6_HUMAN (1-883): 5.66e-32: 139: 13.37
+	Hs
		1061186 PHIP_HUMAN (348-939): 3.6e-54: 209: 13.41		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		299057 PHF14_HUMAN (173-572): 2.71e-54: 207: 17.83		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		1061258 BRD7_HUMAN (487-954): 2.63e-53: 200: 18.15		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		1061156 PB1_HUMAN (351-673): 1.92e-28: 126: 15.92		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		725030 BRD7_HUMAN (487-954): 2.63e-53: 200: 18.15		MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62
+	Hs
		876599 AF17_HUMAN (217-522): 3.72e-53: 205: 28.89		EEA1_HUMAN (964-1838): 2.18e-28: 127: 12.15
+	Hs
		518903 PHIP_HUMAN (348-939): 3.6e-54: 209: 13.41		TPR_HUMAN (2-620): 2.42e-18: 94.7: 12.04