HitPredict

Interactor 1: SRBS2 (O94875)
Sorbin and SH3 domain-containing protein 2 (Arg-binding protein 2) (ArgBP2) (Arg/Abl-interacting protein 2) (Sorbin)
Gene: SORBS2

Interactor 2: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	15778465, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1100 Hs			1 248
+	Hs
		320229 SRBS2_HUMAN (1-1100): 0: 747: 100.00		1433E_HUMAN (2-246): 4.43e-146: 410: 60.41
+	Hs
		320272 SRBS2_HUMAN (1-1100): 0: 747: 100.00		V9HW98_HUMAN (2-246): 4.43e-146: 410: 60.41
+	Hs
		320230 SRBS2_HUMAN (1-1100): 0: 747: 100.00		1433Z_HUMAN (1-242): 8.34e-142: 398: 70.66
+	Mm
		972217 SRBS2_MOUSE (1-1100): 0: 714: 86.74		1433E_MOUSE (2-246): 4.43e-146: 410: 60.41
+	Hs
		320211 SRBS2_HUMAN (1-1100): 0: 747: 100.00		1433T_HUMAN (1-238): 1e-107: 312: 71.85
+	Hs
		320213 SRBS2_HUMAN (1-1100): 0: 747: 100.00		1433B_HUMAN (1-239): 3.42e-100: 293: 68.62
+	Hs
		320227 SRBS2_HUMAN (1-1100): 0: 747: 100.00		1433G_HUMAN (1-242): 1.87e-98: 289: 65.16
+	Hs
		320234 SRBS2_HUMAN (1-1100): 0: 747: 100.00		1433F_HUMAN (2-242): 2.79e-96: 283: 64.20
+	Hs
		730573 SPTN1_HUMAN (86-954): 2.07e-63: 239: 12.34		1433S_HUMAN (1-248): 3.5e-158: 440: 100.00
+	Hs
		971506 SPTN1_HUMAN (86-954): 2.07e-63: 239: 12.34		1433E_HUMAN (2-246): 4.43e-146: 410: 60.41
+	Mm
		464660 SPTA1_MOUSE (86-949): 2.28e-68: 254: 11.39		1433Z_MOUSE (1-243): 1.35e-136: 385: 69.96
+	Hs
		990203 SPTN1_HUMAN (86-954): 2.07e-63: 239: 12.34		1433Z_HUMAN (1-242): 8.34e-142: 398: 70.66
+	Mm
		86340 B9EKJ1_MOUSE (86-954): 2.87e-63: 238: 12.29		1433Z_MOUSE (1-243): 1.35e-136: 385: 69.96
+	Hs
		386440 SPTA1_HUMAN (86-949): 9.2e-84: 301: 12.35		1433T_HUMAN (1-238): 1e-107: 312: 71.85
+	Hs
		729819 SPTN1_HUMAN (86-954): 2.07e-63: 239: 12.34		1433B_HUMAN (1-239): 3.42e-100: 293: 68.62
+	Mm
		86365 B9EKJ1_MOUSE (86-954): 2.87e-63: 238: 12.29		1433B_MOUSE (1-239): 3.75e-99: 290: 68.62
+	Hs
		966295 SPTN1_HUMAN (86-954): 2.07e-63: 239: 12.34		1433G_HUMAN (1-242): 1.87e-98: 289: 65.16
+	Hs
		1049275 SPTN1_HUMAN (86-954): 2.07e-63: 239: 12.34		1433F_HUMAN (2-242): 2.79e-96: 283: 64.20
+	Hs
		250211 VINEX_HUMAN (647-1100): 9.13e-37: 150: 29.27		1433T_HUMAN (1-238): 1e-107: 312: 71.85
+	Hs
		250215 VINEX_HUMAN (647-1100): 9.13e-37: 150: 29.27		1433B_HUMAN (1-239): 3.42e-100: 293: 68.62