HitPredict

Interactor 1: RHBT3 (O94955)
Rho-related BTB domain-containing protein 3 (EC 3.6.1.-)
Gene: RHOBTB3

Interactor 2: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 611 Hs			1 193
+	Hs
		318688 RHBT1_HUMAN (31-611): 4.01e-116: 363: 18.45		RAC3_HUMAN (1-179): 7.81e-75: 225: 57.54
+	Hs
		962445 RHBT2_HUMAN (31-610): 8.82e-97: 313: 18.68		RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71
+	Mm
		953795 CDC42_MOUSE (31-209): 5.13e-74: 236: 18.85		RAC1_MOUSE (1-193): 6.84e-81: 240: 57.22
+	Hs
		955016 CDC42_HUMAN (31-209): 5.13e-74: 236: 18.85		RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71
+	Hs
		955037 CDC42_HUMAN (31-209): 5.13e-74: 236: 18.85		RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22
+	Hs
		466178 CDC42_HUMAN (31-209): 5.13e-74: 236: 18.85		RHOC_HUMAN (1-193): 7.6e-80: 237: 100.00
+	Hs
		955055 CDC42_HUMAN (31-209): 5.13e-74: 236: 18.85		RHOG_HUMAN (1-193): 2.26e-78: 233: 54.92
+	Hs
		962650 KLH20_HUMAN (354-610): 4.22e-66: 229: 16.18		RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71
+	Hs
		955004 CDC42_HUMAN (31-209): 5.13e-74: 236: 18.85		CDC42_HUMAN (1-193): 8.86e-78: 232: 51.30
+	Hs
		580962 CDC42_HUMAN (31-209): 5.13e-74: 236: 18.85		RAC2_HUMAN (1-193): 2.92e-77: 231: 54.12
+	Hs
		953371 CDC42_HUMAN (31-209): 5.13e-74: 236: 18.85		RAC3_HUMAN (1-179): 7.81e-75: 225: 57.54
+	Hs
		955029 CDC42_HUMAN (31-209): 5.13e-74: 236: 18.85		RHOB_HUMAN (1-191): 6.1e-74: 222: 84.82
+	Mm
		988918 RAC1_MOUSE (31-206): 4.29e-66: 216: 20.75		RHOA_MOUSE (1-193): 1.03e-81: 242: 92.23
+	Hs
		988254 RAC1_HUMAN (31-206): 4.29e-66: 216: 20.75		RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22
+	Hs
		988272 RAC1_HUMAN (31-206): 4.29e-66: 216: 20.75		RHOG_HUMAN (1-193): 2.26e-78: 233: 54.92
+	Hs
		580977 RAC1_HUMAN (31-206): 4.29e-66: 216: 20.75		RAC2_HUMAN (1-193): 2.92e-77: 231: 54.12
+	Hs
		953382 RAC1_HUMAN (31-206): 4.29e-66: 216: 20.75		RAC3_HUMAN (1-179): 7.81e-75: 225: 57.54
+	Hs
		977916 RAC1_HUMAN (31-206): 4.29e-66: 216: 20.75		RHOB_HUMAN (1-191): 6.1e-74: 222: 84.82