HitPredict

Interactor 1: BAG2 (O95816)
BAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2)
Gene: BAG2

Interactor 2: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0031397 - negative regulation of protein ubiquitination GO:0032091 - negative regulation of protein binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 211 Hs			1 480
+	Hs
		323543 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		KPCB_HUMAN (14-477): 1.15e-148: 441: 36.67
+	Hs
		324093 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		KS6B2_HUMAN (129-479): 4.6e-147: 430: 42.25
+	Hs
		323575 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		KAPCA_HUMAN (138-445): 1.76e-144: 419: 42.53
+	Hs
		323646 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		KS6A3_HUMAN (36-455): 4.1e-103: 325: 23.01
+	Hs
		323624 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		KPCI_HUMAN (139-474): 7.46e-101: 316: 45.53