Protein: SCAF8
SR-related and CTD-associated factor 8 (CDC5L complex-associated protein 7) (RNA-binding motif protein 16)

Gene: SCAF8
Organism: Homo sapiens
Interactions: 73
UniProt ID: Q9UPN6

Gene Ontology (top 5):
GO:0000993 - RNA polymerase II complex binding
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1199759

KLH22
Kelch-like protein 22

3

4

High-throughput

0.662

High

1436447

MINY3
Ubiquitin carboxyl-terminal hydrolase MINDY-3

3

0

High-throughput

0.638

High

1206030

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

6

High-throughput

0.628

High

1239692

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

2

1

High-throughput

0.628

High

1404514

CDC5L
Cell division cycle 5-like protein

2

3

Small-scale

0.628

High

485516

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

4

High-throughput

0.618

High

1152677

ELAV1
ELAV-like protein 1

1

2

High-throughput

0.618

High

1369874

CELF1
CUGBP Elav-like family member 1

1

5

High-throughput

0.618

High

1459324

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.618

High

1461475

DNPEP
Aspartyl aminopeptidase

2

0

High-throughput

0.585

High

485761

RU2A
U2 small nuclear ribonucleoprotein A'

1

4

High-throughput

0.575

High

1145439

RNPS1
RNA-binding protein with serine-rich domain 1

1

3

High-throughput

0.575

High

1063701

GOGA2
Golgin subfamily A member 2

2

3

High-throughput

0.573

High

397227

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

281457

GGYF1
GRB10-interacting GYF protein 1

2

2

High-throughput

0.553

High

123876

MYO1C
Unconventional myosin-Ic

1

5

High-throughput

0.536

High

575219

IDE
Insulin-degrading enzyme

1

2

High-throughput

0.536

High

692839

CALL3
Calmodulin-like protein 3

1

10

High-throughput

0.536

High

766011

BMI1
Polycomb complex protein BMI-1

1

3

High-throughput

0.536

High

1136414

EMC2
ER membrane protein complex subunit 2

1

4

High-throughput

0.536

High

1367916

THRSP
Thyroid hormone-inducible hepatic protein

1

0

High-throughput

0.513

High

1451551

PLAT2
Phospholipase A and acyltransferase 2

1

0

High-throughput

0.513

High

533069

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.493

High

143329

NFIB
Nuclear factor 1 B-type

1

13

High-throughput

0.479

High

320149

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

323609

TRI37
E3 ubiquitin-protein ligase TRIM37

1

13

High-throughput

0.479

High

474376

NFIC
Nuclear factor 1 C-type

1

17

High-throughput

0.479

High

621795

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.479

High

879618

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

4

High-throughput

0.479

High

1045913

TF65
Transcription factor p65

1

6

High-throughput

0.479

High

1048136

TLE3
Transducin-like enhancer protein 3

1

7

High-throughput

0.479

High

1088102

NFIA
Nuclear factor 1 A-type

1

19

High-throughput

0.479

High

1121920

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

9

High-throughput

0.479

High

1133738

NFIX
Nuclear factor 1 X-type

1

18

High-throughput

0.479

High

1138757

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

1156902

E2F4
Transcription factor E2F4

1

4

High-throughput

0.479

High

1256110

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.479

High

1289338

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

5

High-throughput

0.479

High

1339233

NUP35
Nucleoporin NUP35

1

1

High-throughput

0.479

High

1351199

SP7
Transcription factor Sp7

1

5

High-throughput

0.479

High

1387645

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

7

High-throughput

0.479

High

1434242

PKHA4
Pleckstrin homology domain-containing family A member 4

1

11

High-throughput

0.479

High

1448789

RNC
Ribonuclease 3

1

5

High-throughput

0.479

High

1453175

WWOX
WW domain-containing oxidoreductase

1

3

High-throughput

0.479

High

1462496

TRRAP
Transformation/transcription domain-associated protein

1

3

High-throughput

0.479

High

1364014

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

1365393

CNOT9
CCR4-NOT transcription complex subunit 9

1

0

High-throughput

0.458

High

1393827

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1420632

IN80B
INO80 complex subunit B

1

0

High-throughput

0.458

High

1435458

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

290798

SURF6
Surfeit locus protein 6

1

1

High-throughput

0.445

High

429059

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.445

High

430514

JUN
Transcription factor Jun

1

10

High-throughput

0.445

High

480355

RU1C
U1 small nuclear ribonucleoprotein C

1

2

High-throughput

0.445

High

584165

FOSL2
Fos-related antigen 2

1

1

High-throughput

0.445

High

649456

H1T
Histone H1t

1

2

High-throughput

0.445

High

686524

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.445

High

809920

RS19
Small ribosomal subunit protein eS19

1

2

High-throughput

0.445

High

967609

RS7
Small ribosomal subunit protein eS7

1

1

High-throughput

0.445

High

972615

RS14
Small ribosomal subunit protein uS11

1

2

High-throughput

0.445

High

412814

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.437

High

1445967

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

3

High-throughput

0.437

High

1461697

HECD1
E3 ubiquitin-protein ligase HECTD1

1

6

Small-scale

0.437

High

1128154

DHX8
ATP-dependent RNA helicase DHX8

1

0

High-throughput

0.426

High

1337436

SRFB1
Serum response factor-binding protein 1

1

0

High-throughput

0.426

High

1352998

CE192
Centrosomal protein of 192 kDa

1

0

High-throughput

0.426

High

1451830

LYAR
Cell growth-regulating nucleolar protein

1

0

High-throughput

0.426

High

142443

PEX7
Peroxisomal targeting signal 2 receptor

1

7

High-throughput

0.407

High

1460549

NAGK
N-acetyl-D-glucosamine kinase

2

0

High-throughput

0.328

High

1315008

TEX11
Testis-expressed protein 11

2

0

High-throughput

0.316

High

1326952

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.279

Low

1418524

ACE2
Angiotensin-converting enzyme 2

1

0

Small-scale

0.249

Low

62614

S35F4
Solute carrier family 35 member F4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025