HitPredict

Interactor 1: SNAI1 (O95863)
Zinc finger protein SNAI1 (Protein snail homolog 1) (Protein sna)
Gene: SNAI1

Interactor 2: RO52 (P19474)
E3 ubiquitin-protein ligase TRIM21 (EC 2.3.2.27) (52 kDa Ro protein) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (RING finger protein 81) (Ro(SS-A)) (Sjoegren syndrome type A antigen) (SS-A) (Tripartite motif-containing protein 21)
Gene: TRIM21

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.664

Property	Details
Experiments	30502437, 31622717, 29331416
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 264 Hs			1 475
+	Hs
		326414 SNAI1_HUMAN (1-264): 1.39e-81: 247: 100.00		TRI27_HUMAN (1-466): 2.88e-141: 416: 37.17
+	Hs
		536846 ZNF79_HUMAN (2-176): 7.49e-78: 245: 12.16		TRI27_HUMAN (1-466): 2.88e-141: 416: 37.17
+	Hs
		1336387 ZN214_HUMAN (66-263): 1.17e-63: 211: 24.88		TRI39_HUMAN (7-469): 3.45e-150: 440: 38.32
+	Hs
		1238810 ZN383_HUMAN (3-152): 1.09e-63: 208: 7.74		TRI39_HUMAN (7-469): 3.45e-150: 440: 38.32
+	Hs
		326703 SNAI1_HUMAN (1-264): 1.39e-81: 247: 100.00		TRI50_HUMAN (1-461): 1.37e-120: 363: 26.74
+	Hs
		326772 SNAI1_HUMAN (1-264): 1.39e-81: 247: 100.00		TRIM5_HUMAN (1-466): 9.08e-121: 363: 40.04
+	Hs
		536720 ZN250_HUMAN (4-151): 1.59e-56: 191: 7.19		TRI27_HUMAN (1-466): 2.88e-141: 416: 37.17
+	Hs
		536912 ZSC29_HUMAN (142-263): 3.05e-49: 175: 35.48		TRI27_HUMAN (1-466): 2.88e-141: 416: 37.17
+	Hs
		1242707 ZN248_HUMAN (9-178): 1.34e-33: 129: 10.80		TRI39_HUMAN (7-469): 3.45e-150: 440: 38.32
+	Hs
		997546 ZN543_HUMAN (3-87): 1.48e-26: 109: 5.88		TRI39_HUMAN (7-469): 3.45e-150: 440: 38.32
+	Hs
		1281575 ZKSC4_HUMAN (87-206): 8.51e-21: 93.1: 18.18		TRI39_HUMAN (7-469): 3.45e-150: 440: 38.32
+	Hs
		1167074 ZN562_HUMAN (148-254): 6.34e-14: 72.8: 28.47		TRI39_HUMAN (7-469): 3.45e-150: 440: 38.32
+	Hs
		1261114 ZNF71_HUMAN (26-263): 9.61e-105: 314: 22.76		TRI41_HUMAN (1-44): 3.5e-10: 64.1: 45.83
+	Hs
		1169140 ZFP2_HUMAN (5-263): 3.07e-95: 288: 21.40		TRI41_HUMAN (1-44): 3.5e-10: 64.1: 45.83
+	Hs
		1158942 ZFP1_HUMAN (3-263): 1.44e-85: 262: 21.56		TRI41_HUMAN (1-44): 3.5e-10: 64.1: 45.83
+	Hs
		549202 ZN250_HUMAN (4-151): 1.59e-56: 191: 7.19		TRI41_HUMAN (1-44): 3.5e-10: 64.1: 45.83
+	Hs
		1261083 ZN251_HUMAN (2-170): 7.75e-50: 175: 9.14		TRI41_HUMAN (1-44): 3.5e-10: 64.1: 45.83
+	Hs
		836602 ZN165_HUMAN (142-263): 4.09e-28: 113: 18.39		TRI41_HUMAN (1-44): 3.5e-10: 64.1: 45.83
+	Hs
		1167072 ZN562_HUMAN (148-254): 6.34e-14: 72.8: 28.47		TRI41_HUMAN (1-44): 3.5e-10: 64.1: 45.83
+	Hs
		885474 ZN121_HUMAN (150-230): 3.85e-13: 70.5: 43.37		TRI41_HUMAN (1-44): 3.5e-10: 64.1: 45.83