HitPredict

Interactor 1: TOM40 (O96008)
Mitochondrial import receptor subunit TOM40 homolog (Protein Haymaker) (Translocase of outer membrane 40 kDa subunit homolog) (p38.5)
Gene: TOMM40

Interactor 2: PINK1 (Q9BXM7)
Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Gene: PINK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	28438176, 30783609, 33961781, 22280891
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0005743 - mitochondrial inner membrane GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 361 Hs			1 581
+	Hs
		800063 VDAC2_HUMAN (67-360): 7.67e-85: 260: 10.82		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		601350 VDAC1_HUMAN (77-359): 5.38e-75: 235: 12.93		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		799974 VDAC2_HUMAN (67-360): 7.67e-85: 260: 10.82		KPCZ_HUMAN (54-568): 6.17e-114: 353: 13.97
+	Hs
		568578 VDAC2_HUMAN (67-360): 7.67e-85: 260: 10.82		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89
+	Hs
		568835 VDAC3_HUMAN (77-360): 1.86e-84: 259: 9.97		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89
+	Hs
		601224 VDAC1_HUMAN (77-359): 5.38e-75: 235: 12.93		KPCZ_HUMAN (54-568): 6.17e-114: 353: 13.97
+	Hs
		568538 VDAC1_HUMAN (77-359): 5.38e-75: 235: 12.93		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89