Interactor 1: CHK2 (O96017)
Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)
Gene: CHEK2

Interactor 2: ELAV1 (Q15717)
ELAV-like protein 1 (Hu-antigen R) (HuR)
Gene: ELAVL1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.756

The method score is based on:

Property Details
Experiments 17317627
Identification Methods affinity chromatography technology, two hybrid, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~RRM_1
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0019901 - protein kinase binding
GO:0042803 - protein homodimerization activity
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 543
Hs

1 326
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs

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Last updated: 15 Jul 2024