Interactor 1: ARI2 (O95376)
E3 ubiquitin-protein ligase ARIH2 (ARI-2) (Protein ariadne-2 homolog) (EC 2.3.2.31) (Triad1 protein)
Gene: ARIH2

Interactor 2: PML (P29590)
Protein PML (E3 SUMO-protein ligase PML) (EC 2.3.2.-) (Promyelocytic leukemia protein) (RING finger protein 71) (RING-type E3 SUMO transferase PML) (Tripartite motif-containing protein 19) (TRIM19)
Gene: PML

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 22037423
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ariadne~zf-C3HC4, IBR~zf-C3HC4, zf-C3HC4~zf-C3HC4
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0008270 - zinc ion binding
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 493
Hs

1 882
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Service provided by Combinatics, Japan

Last updated: 11Aug2025