HitPredict

Interactor 1: SODC (P00441)
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1) (Superoxide dismutase 1) (hSod1)
Gene: SOD1

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	29128334
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 154 Hs			1 247
+	Hs
		336452 SODC_HUMAN (1-154): 8.73e-72: 214: 100.00		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Mm
		437605 SODC_MOUSE (1-154): 3.51e-71: 212: 83.77		1433G_MOUSE (1-247): 3.15e-139: 392: 100.00
+	Mm
		437609 SODC_MOUSE (1-154): 3.51e-71: 212: 83.77		1433F_MOUSE (1-246): 1.51e-136: 385: 86.99
+	Hs
		336385 SODC_HUMAN (1-154): 8.73e-72: 214: 100.00		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		336461 SODC_HUMAN (1-154): 8.73e-72: 214: 100.00		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Mm
		437607 SODC_MOUSE (1-154): 3.51e-71: 212: 83.77		1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59
+	Mm
		437623 SODC_MOUSE (1-154): 3.51e-71: 212: 83.77		1433B_MOUSE (2-247): 8.57e-109: 315: 75.81
+	Hs
		336370 SODC_HUMAN (1-154): 8.73e-72: 214: 100.00		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Mm
		437608 SODC_MOUSE (1-154): 3.51e-71: 212: 83.77		1433T_MOUSE (2-245): 3e-105: 306: 70.73