HitPredict

Interactor 1: SNP29 (O95721)
Synaptosomal-associated protein 29 (SNAP-29) (Soluble 29 kDa NSF attachment protein) (Vesicle-membrane fusion protein SNAP-29)
Gene: SNAP29

Interactor 2: STX4 (Q12846)
Syntaxin-4 (Renal carcinoma antigen NY-REN-31)
Gene: STX4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	34079125, 9852078, 33961781
Identification Methods	proximity labelling technology, pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006887 - exocytosis GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 258 Hs			1 297
+	Hs
		343346 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		STX1B_HUMAN (1-295): 1.57e-72: 226: 46.28
+	Hs
		343322 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		STX2_HUMAN (1-295): 4.49e-72: 225: 42.57
+	Hs
		343380 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		STX1A_HUMAN (1-293): 1.91e-70: 221: 43.20
+	Mm
		204936 SNP29_MOUSE (1-258): 2.07e-81: 246: 83.08		STX1A_MOUSE (1-293): 8.06e-72: 224: 43.54
+	Hs
		343369 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		STX3_HUMAN (1-295): 6.66e-57: 186: 38.31
+	Hs
		343513 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		X5D7S1_HUMAN (1-294): 1.05e-56: 184: 37.42
+	Hs
		286615 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		STX11_HUMAN (1-282): 4.23e-53: 176: 27.18
+	Hs
		160857 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		STX16_HUMAN (6-272): 8.9e-51: 171: 20.45
+	Hs
		189367 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		STX7_HUMAN (31-291): 4.49e-50: 167: 23.95
+	Hs
		343406 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		STX12_HUMAN (34-279): 2.36e-49: 166: 25.00
+	Hs
		124030 SNP23_HUMAN (41-258): 1.15e-58: 187: 20.18		STX1B_HUMAN (1-295): 1.57e-72: 226: 46.28
+	Hs
		123997 SNP23_HUMAN (41-258): 1.15e-58: 187: 20.18		STX2_HUMAN (1-295): 4.49e-72: 225: 42.57
+	Hs
		124045 SNP23_HUMAN (41-258): 1.15e-58: 187: 20.18		STX4_HUMAN (1-297): 3.02e-70: 221: 100.00
+	Hs
		124048 SNP23_HUMAN (41-258): 1.15e-58: 187: 20.18		STX3_HUMAN (1-295): 6.66e-57: 186: 38.31
+	Hs
		123952 SNP23_HUMAN (41-258): 1.15e-58: 187: 20.18		STX11_HUMAN (1-282): 4.23e-53: 176: 27.18
+	Hs
		69431 A8K287_HUMAN (41-258): 1.15e-58: 187: 20.18		STX11_HUMAN (1-282): 4.23e-53: 176: 27.18
+	At
		1192496 SNP29_ARATH (1-258): 2.54e-60: 192: 21.85		SY111_ARATH (7-274): 5.34e-50: 169: 17.22
+	Hs
		123944 SNP23_HUMAN (41-258): 1.15e-58: 187: 20.18		STX7_HUMAN (31-291): 4.49e-50: 167: 23.95
+	Hs
		48186 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		A0AVG3_HUMAN (37-295): 1.17e-22: 99.4: 17.16
+	Hs
		343448 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		TSNA1_HUMAN (37-295): 6.39e-22: 97.1: 16.48