HitPredict

Interactor 1: CYTA (P01040)
Cystatin-A (Cystatin-AS) (Stefin-A) [Cleaved into: Cystatin-A, N-terminally processed]
Gene: CSTA

Interactor 2: CATH (P09668)
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H (EC 3.4.22.16); Cathepsin H heavy chain; Cathepsin H light chain]
Gene: CTSH

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	12581647, 33961781
Identification Methods	x-ray crystallography, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	Cystatin~Peptidase_C1
Common GO terms	GO:0005615 - extracellular space GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 98 Hs			1 335
+	Hs
		376061 CYTB_HUMAN (1-98): 7.38e-54: 164: 53.06		CATH_HUMAN (1-335): 1.11e-163: 461: 100.00
+	Hs
		376059 CYTB_HUMAN (1-98): 7.38e-54: 164: 53.06		CATL1_HUMAN (6-332): 3.32e-144: 411: 37.39
+	Hs
		245771 CYTA_HUMAN (1-98): 2.93e-49: 152: 100.00		CATL2_HUMAN (8-331): 5.29e-145: 414: 38.62
+	Hs
		345044 CYTA_HUMAN (1-98): 2.93e-49: 152: 100.00		CATL1_HUMAN (6-332): 3.32e-144: 411: 37.39
+	Hs
		376119 CYTB_HUMAN (1-98): 7.38e-54: 164: 53.06		CATF_HUMAN (35-332): 9.57e-110: 329: 36.30
+	Hs
		345149 CYTA_HUMAN (1-98): 2.93e-49: 152: 100.00		CATF_HUMAN (35-332): 9.57e-110: 329: 36.30