HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: DEST (P60981)
Destrin (Actin-depolymerizing factor) (ADF)
Gene: DSTN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29467282, 35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 165
+	Hs
		345945 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		COF1_HUMAN (1-165): 5.13e-70: 210: 71.08
+	Hs
		346640 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TWF1_HUMAN (3-152): 1.54e-37: 133: 20.26
+	Hs
		347051 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TWF2_HUMAN (3-152): 3.92e-31: 116: 18.30
+	Hs
		379186 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DEST_HUMAN (1-165): 6.05e-74: 220: 100.00
+	Hs
		379025 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		COF1_HUMAN (1-165): 5.13e-70: 210: 71.08