HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: GOGA2 (Q08379)
Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein) (GM130) (GM130 autoantigen) (Golgin-95)
Gene: GOLGA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	25416956
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000922 - spindle pole GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1130 Hs			1 1002
+	Hs
		349288 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH13_HUMAN (442-989): 3.16e-24: 112: 11.44
+	Hs
		348952 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH7_HUMAN (17-573): 4.92e-22: 105: 11.13
+	Hs
		348955 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH8_HUMAN (483-973): 8.25e-22: 104: 10.37
+	Hs
		348954 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH6_HUMAN (483-965): 8.38e-21: 101: 9.32
+	Hs
		349307 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH4_HUMAN (1-543): 4.62e-18: 92.5: 9.51
+	Hs
		349287 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH2_HUMAN (1-362): 9.41e-12: 71.7: 10.99
+	Hs
		348951 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH1_HUMAN (1-362): 1.27e-11: 71.3: 11.53
+	Hs
		348948 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH3_HUMAN (695-974): 2.78e-11: 70.1: 12.01
+	Hs
		349270 LATS1_HUMAN (1-1130): 0: 925: 100.00		DAPLE_HUMAN (220-878): 3.64e-10: 66.7: 14.39
+	Hs
		157903 LATS2_HUMAN (13-1121): 0: 742: 49.52		CTRO_HUMAN (77-749): 7.55e-21: 101: 12.22
+	Hs
		1448694 LATS2_HUMAN (13-1121): 0: 742: 49.52		DAPLE_HUMAN (220-878): 3.64e-10: 66.7: 14.39
+	Hs
		773091 ST38L_HUMAN (627-1089): 1.01e-161: 489: 40.82		MYH9_HUMAN (380-978): 2.78e-26: 119: 11.04
+	Hs
		728066 AKT1_HUMAN (595-1079): 1.92e-140: 434: 24.60		MYH9_HUMAN (380-978): 2.78e-26: 119: 11.04
+	Hs
		605577 KAPCA_HUMAN (661-1058): 1.57e-137: 421: 31.59		MYH9_HUMAN (380-978): 2.78e-26: 119: 11.04
+	Hs
		605578 KAPCA_HUMAN (661-1058): 1.57e-137: 421: 31.59		MYH10_HUMAN (555-993): 4.54e-19: 95.5: 11.06
+	Hs
		562995 KAPCB_HUMAN (661-1055): 6.64e-133: 409: 31.58		MYH6_HUMAN (483-965): 8.38e-21: 101: 9.32
+	Hs
		651743 KAPCB_HUMAN (661-1055): 6.64e-133: 409: 31.58		MYH4_HUMAN (1-543): 4.62e-18: 92.5: 9.51
+	Hs
		651734 KAPCB_HUMAN (661-1055): 6.64e-133: 409: 31.58		MYH2_HUMAN (1-362): 9.41e-12: 71.7: 10.99
+	Hs
		556840 KAPCB_HUMAN (661-1055): 6.64e-133: 409: 31.58		MYH1_HUMAN (1-362): 1.27e-11: 71.3: 11.53
+	Hs
		772782 ROCK1_HUMAN (694-1046): 9.27e-66: 245: 39.94		MYH9_HUMAN (380-978): 2.78e-26: 119: 11.04