HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: NIN (Q8N4C6)
Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein)
Gene: NIN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	28718761, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000922 - spindle pole GO:0005813 - centrosome GO:0008104 - intracellular protein localization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1130 Hs			1 2090
+	Hs
		1326358 LATS2_HUMAN (13-1121): 0: 742: 49.52		NIN_HUMAN (1-2090): 0: 608: 100.00
+	Hs
		349085 LATS1_HUMAN (1-1130): 0: 925: 100.00		PLEC_HUMAN (108-1476): 9.56e-39: 162: 12.64
+	Hs
		348955 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH8_HUMAN (4-1070): 1.19e-32: 141: 12.30
+	Hs
		176920 LATS1_HUMAN (1-1130): 0: 925: 100.00		CE290_HUMAN (10-1207): 1.36e-23: 112: 11.72
+	Hs
		348954 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH6_HUMAN (41-959): 2.96e-23: 110: 12.16
+	Hs
		349288 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH13_HUMAN (63-770): 6.04e-20: 100: 10.73
+	Hs
		348952 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH7_HUMAN (1382-2069): 2.3e-15: 84.8: 14.31
+	Hs
		348948 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH3_HUMAN (1627-2089): 8.47e-15: 83.1: 10.99
+	Hs
		348951 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH1_HUMAN (1326-2059): 8.08e-14: 79.7: 12.59
+	Hs
		349298 LATS1_HUMAN (1-1130): 0: 925: 100.00		NINL_HUMAN (932-2088): 2.06e-10: 68.5: 9.06
+	Hs
		349287 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH2_HUMAN (596-1675): 9.69e-10: 66.3: 18.02
+	Hs
		1448720 LATS2_HUMAN (13-1121): 0: 742: 49.52		NINL_HUMAN (932-2088): 2.06e-10: 68.5: 9.06
+	Hs
		773091 ST38L_HUMAN (627-1089): 1.01e-161: 489: 40.82		MYH9_HUMAN (36-1167): 1.64e-38: 160: 10.73
+	Hs
		728066 AKT1_HUMAN (595-1079): 1.92e-140: 434: 24.60		MYH9_HUMAN (36-1167): 1.64e-38: 160: 10.73
+	Hs
		605577 KAPCA_HUMAN (661-1058): 1.57e-137: 421: 31.59		MYH9_HUMAN (36-1167): 1.64e-38: 160: 10.73
+	Dm
		1303781 WARTS_DROME (161-1065): 2.61e-150: 480: 39.48		Q8INC3_DROME (413-1072): 1.12e-13: 79.4: 20.31
+	Dm
		1070923 WARTS_DROME (161-1065): 2.61e-150: 480: 39.48		Q0KI67_DROME (413-1072): 2.45e-13: 78.3: 20.31
+	Hs
		587568 AKT1_HUMAN (595-1079): 1.92e-140: 434: 24.60		DESP_HUMAN (1122-2071): 1.9e-15: 85.1: 11.54
+	Hs
		552745 KAPCA_HUMAN (661-1058): 1.57e-137: 421: 31.59		TPR_HUMAN (1-842): 1.87e-18: 95.1: 10.29
+	Hs
		605578 KAPCA_HUMAN (661-1058): 1.57e-137: 421: 31.59		MYH10_HUMAN (1611-2090): 1.9e-15: 85: 11.11