HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: DSC2 (Q02487)
Desmocollin-2 (Cadherin family member 2) (Desmocollin-3) (Desmosomal glycoprotein II) (Desmosomal glycoprotein III)
Gene: DSC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 901
+	Hs
		348626 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		DSC2_HUMAN (1-901): 0: 855: 100.00
+	Hs
		350090 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		DSC2_HUMAN (1-901): 0: 855: 100.00
+	Hs
		914018 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		DSC2_HUMAN (1-901): 0: 855: 100.00
+	Hs
		348666 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		DSC3_HUMAN (1-901): 0: 806: 66.70
+	Hs
		350172 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		DSC3_HUMAN (1-901): 0: 806: 66.70
+	Hs
		349322 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		DSC3_HUMAN (1-901): 0: 806: 66.70
+	Hs
		349835 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		CADH1_HUMAN (28-897): 0: 714: 28.09
+	Hs
		521847 RAB1A_HUMAN (4-186): 2.67e-75: 226: 31.28		CADH1_HUMAN (28-897): 0: 714: 28.09
+	Hs
		522113 RAB8B_HUMAN (4-180): 8.57e-74: 222: 36.31		CADH1_HUMAN (28-897): 0: 714: 28.09
+	Hs
		349094 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		CADH1_HUMAN (28-897): 0: 714: 28.09
+	Hs
		521957 RB11B_HUMAN (4-171): 1.34e-72: 219: 34.12		CADH1_HUMAN (28-897): 0: 714: 28.09
+	Hs
		580251 RAB8B_HUMAN (4-180): 8.57e-74: 222: 36.31		CADH2_HUMAN (4-385): 1.04e-51: 197: 15.55
+	Hs
		919689 RAP1A_HUMAN (1-165): 3.2e-62: 192: 56.89		PCDA8_HUMAN (358-864): 2.34e-50: 193: 13.02
+	Hs
		1079934 RB11B_HUMAN (4-171): 1.34e-72: 219: 34.12		DSG4_HUMAN (20-372): 1.22e-32: 138: 17.84
+	Hs
		348660 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		DSG2_HUMAN (69-401): 2e-20: 99.3: 17.18
+	Hs
		350163 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		DSG2_HUMAN (69-401): 2e-20: 99.3: 17.18
+	Hs
		914063 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		DSG2_HUMAN (69-401): 2e-20: 99.3: 17.18
+	Hs
		349315 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		DSG2_HUMAN (69-401): 2e-20: 99.3: 17.18
+	Cl
		94527 RAB1A_CANLF (4-186): 2.67e-75: 226: 31.28		CADH1_CANLF (24-261): 1.71e-16: 86.6: 15.30