HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: UBP8 (P50102)
Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8)
Gene: UBP8

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.602

Property	Details
Experiments	36965704, 20434206
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 131 Sc			1 471
+	Sc
		355943 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		UBP8_YEAST (1-471): 1.09e-160: 464: 100.00
+	Hs
		1087489 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		UBP22_HUMAN (4-471): 1.09e-124: 374: 26.96
+	Hs
		707794 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP22_HUMAN (4-471): 1.09e-124: 374: 26.96
+	Hs
		707665 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP51_HUMAN (4-471): 1.1e-119: 367: 26.49
+	Hs
		1087411 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		UBP42_HUMAN (30-467): 1.44e-107: 349: 23.88
+	Hs
		241654 H2B1K_HUMAN (7-128): 1.06e-45: 146: 70.16		UBP36_HUMAN (85-467): 4.65e-100: 325: 24.75
+	Hs
		420891 H2B1J_HUMAN (7-128): 5.77e-46: 146: 70.16		UBP36_HUMAN (85-467): 4.65e-100: 325: 24.75
+	Hs
		707772 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP36_HUMAN (85-467): 4.65e-100: 325: 24.75
+	Hs
		777048 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		UBP8_HUMAN (131-465): 2.44e-99: 323: 29.49
+	Hs
		271037 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP2_HUMAN (115-466): 9.24e-103: 320: 27.20
+	Hs
		707807 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP3_HUMAN (23-470): 2.77e-102: 317: 24.43
+	Hs
		707785 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP21_HUMAN (94-470): 2.58e-99: 310: 24.04
+	Hs
		259286 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		UBP12_HUMAN (136-469): 2.48e-96: 296: 27.30
+	Hs
		1087318 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		UBP7_HUMAN (49-467): 8.36e-89: 294: 21.09
+	Hs
		707705 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP7_HUMAN (49-467): 8.36e-89: 294: 21.09
+	Hs
		905383 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		UBP46_HUMAN (136-469): 1.37e-94: 292: 26.74
+	Hs
		905394 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		UBP46_HUMAN (136-469): 1.37e-94: 292: 26.74
+	Hs
		1121182 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		UBP39_HUMAN (18-471): 2.99e-89: 284: 17.96
+	Hs
		1087213 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		UBP49_HUMAN (135-470): 7.3e-33: 134: 28.50
+	Hs
		707745 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		UBP44_HUMAN (111-468): 1.32e-31: 130: 28.28