HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: ITC1 (P53125)
Imitation switch two complex protein 1
Gene: ITC1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	16429126, 37968396, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 131 Sc			1 1264
+	Sc
		355949 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		ITC1_YEAST (1-1264): 0: 1736: 100.00
+	Hs
		1087428 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		BAZ1A_HUMAN (1-445): 1.22e-102: 359: 20.65
+	Hs
		707763 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		BAZ1A_HUMAN (1-445): 1.22e-102: 359: 20.65
+	Hs
		918717 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		BAZ1A_HUMAN (1-445): 1.22e-102: 359: 20.65
+	Hs
		1087464 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		BAZ1B_HUMAN (2-339): 3.02e-83: 301: 19.68
+	Hs
		1274471 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		BAZ1B_HUMAN (2-339): 3.02e-83: 301: 19.68
+	Hs
		918761 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		BAZ1B_HUMAN (2-339): 3.02e-83: 301: 19.68
+	Hs
		886214 H2B1D_HUMAN (7-128): 1.99e-45: 145: 70.16		BAZ1B_HUMAN (2-339): 3.02e-83: 301: 19.68
+	Hs
		1307152 H2B1L_HUMAN (7-128): 2.46e-44: 142: 70.16		BAZ1B_HUMAN (2-339): 3.02e-83: 301: 19.68
+	Dm
		355270 H2B_DROME (8-128): 2.21e-45: 145: 67.77		Q9V9T4_DROME (1-439): 1.24e-48: 192: 18.28