HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: NHP10 (Q03435)
Non-histone protein 10 (High mobility group protein 2)
Gene: NHP10

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21179020
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 131 Sc			1 203
+	Hs
		241615 H2B1K_HUMAN (7-128): 1.06e-45: 146: 70.16		CIC_HUMAN (44-201): 6.64e-29: 114: 16.76
+	Hs
		297497 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		TOX4_HUMAN (51-199): 4.76e-28: 112: 18.82
+	Ce
		136643 H2B1_CAEEL (9-128): 2.33e-47: 150: 72.50		SSP1B_CAEEL (90-192): 1.05e-25: 105: 27.62
+	Ce
		136714 H2B4_CAEEL (8-128): 6.29e-47: 149: 71.90		SSP1B_CAEEL (90-192): 1.05e-25: 105: 27.62
+	Hs
		996694 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		SSRP1_HUMAN (72-186): 2.34e-26: 107: 21.85
+	Hs
		996812 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		SSRP1_HUMAN (72-186): 2.34e-26: 107: 21.85
+	Hs
		420830 H2B1J_HUMAN (7-128): 5.77e-46: 146: 70.16		SSRP1_HUMAN (72-186): 2.34e-26: 107: 21.85
+	Hs
		918316 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		SSRP1_HUMAN (72-186): 2.34e-26: 107: 21.85
+	Hs
		996768 H2B3B_HUMAN (7-128): 2.3e-44: 143: 64.52		SSRP1_HUMAN (72-186): 2.34e-26: 107: 21.85
+	Sc
		355755 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		NHP6A_YEAST (78-162): 3.8e-25: 95.6: 31.46
+	Sc
		355756 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		NHP6B_YEAST (78-162): 4.26e-25: 95.6: 32.58
+	Hs
		175767 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		HMGB3_HUMAN (90-160): 1.02e-23: 94.9: 32.00
+	Sc
		355313 H2B1_YEAST (1-131): 2.54e-44: 143: 100.00		NHP6A_YEAST (78-162): 3.8e-25: 95.6: 31.46
+	Sc
		355314 H2B1_YEAST (1-131): 2.54e-44: 143: 100.00		NHP6B_YEAST (78-162): 4.26e-25: 95.6: 32.58
+	Hs
		449786 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		HMGB1_HUMAN (80-160): 1.31e-19: 84.5: 31.77
+	Hs
		643380 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		HMGB2_HUMAN (92-160): 6.72e-16: 74.5: 27.40
+	Hs
		643248 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		HMGB2_HUMAN (92-160): 6.72e-16: 74.5: 27.40
+	Hs
		643302 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		HMGB2_HUMAN (92-160): 6.72e-16: 74.5: 27.40
+	Hs
		996816 H2B1A_HUMAN (29-128): 2.91e-32: 112: 80.00		SSRP1_HUMAN (72-186): 2.34e-26: 107: 21.85