HitPredict

Interactor 1: HSP27 (P02518)
Heat shock protein 27
Gene: HSP27

Interactor 2: HSP72 (Q8INI8)
Major heat shock 70 kDa protein Ba (Heat shock protein 70Ba) (HSP70-87C1)
Gene: Hsp70Ba

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0009408 - response to heat GO:0042026 - protein refolding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 213 Dm			1 641
+	Dm
		385006 HSP27_DROME (1-213): 1.43e-71: 218: 100.00		HSP74_DROME (1-641): 0: 961: 99.84
+	Dm
		384974 HSP27_DROME (1-213): 1.43e-71: 218: 100.00		HSP71_DROME (1-641): 0: 956: 98.29
+	Dm
		384983 HSP27_DROME (1-213): 1.43e-71: 218: 100.00		HSP70_DROME (1-641): 0: 956: 98.29
+	Dm
		356610 HSP27_DROME (1-213): 1.43e-71: 218: 100.00		HSP68_DROME (1-641): 0: 927: 80.81
+	Dm
		384885 HSP26_DROME (1-207): 3.83e-57: 181: 42.45		HSP71_DROME (1-641): 0: 956: 98.29
+	Dm
		384894 HSP26_DROME (1-207): 3.83e-57: 181: 42.45		HSP70_DROME (1-641): 0: 956: 98.29
+	Hs
		415301 HSPB1_HUMAN (4-198): 7.4e-59: 185: 27.78		HSP7C_HUMAN (2-641): 0: 943: 74.18
+	Dm
		384792 HSP23_DROME (33-207): 4.08e-51: 165: 47.51		HSP71_DROME (1-641): 0: 956: 98.29
+	Dm
		384798 HSP23_DROME (33-207): 4.08e-51: 165: 47.51		HSP70_DROME (1-641): 0: 956: 98.29
+	Hs
		384615 CRYAB_HUMAN (13-184): 6.23e-47: 154: 31.98		HSP7C_HUMAN (2-641): 0: 943: 74.18
+	Dm
		356609 HSP23_DROME (33-207): 4.08e-51: 165: 47.51		HSP68_DROME (1-641): 0: 927: 80.81
+	Dm
		384771 HSP22_DROME (31-198): 1.99e-35: 124: 35.09		HSP72_DROME (1-641): 0: 962: 100.00
+	Dm
		384758 HSP22_DROME (31-198): 1.99e-35: 124: 35.09		HSP71_DROME (1-641): 0: 956: 98.29
+	Dm
		384762 HSP22_DROME (31-198): 1.99e-35: 124: 35.09		HSP70_DROME (1-641): 0: 956: 98.29
+	Hs
		1198801 HSPB8_HUMAN (4-167): 2.22e-38: 133: 27.84		Q53FC7_HUMAN (3-641): 0: 939: 70.94
+	Mm
		989277 HSPB2_MOUSE (4-164): 1.17e-35: 125: 28.57		HSP7C_MOUSE (2-641): 0: 942: 74.18
+	Dm
		356608 HSP22_DROME (31-198): 1.99e-35: 124: 35.09		HSP68_DROME (1-641): 0: 927: 80.81