Interactor 1: KGP1 (P00516)
cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI)
Gene: PRKG1
Interactor 2: KGP1 (P00516)
cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI)
Gene: PRKG1
Species: Bos taurus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.692 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21893290 |
| Identification Methods | x-ray crystallography, comigration in non denaturing gel electrophoresis |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | cNMP_binding~cNMP_binding, Pkinase~cNMP_binding, PKcGMP_CC~PKcGMP_CC, Pkinase~Pkinase |
| Common GO terms | GO:0004692 - cGMP-dependent protein kinase activity GO:0005246 - calcium channel regulator activity GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol and 5 others more... |
| Homologous interactions | 17 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
