Interactor 1: ANT3 (P01008)
Antithrombin-III (ATIII) (Serpin C1)
Gene: SERPINC1
Interactor 2: AACT (P01011)
Alpha-1-antichymotrypsin (ACT) (Cell growth-inhibiting gene 24/25 protein) (Serpin A3) [Cleaved into: Alpha-1-antichymotrypsin His-Pro-less]
Gene: SERPINA3
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 37343697 |
| Identification Methods | cross-linking study |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Serpin~Serpin |
| Common GO terms | GO:0004867 - serine-type endopeptidase inhibitor activity GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0070062 - extracellular exosome GO:0072562 - blood microparticle |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
