HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: MYL6 (P60660)
Myosin light polypeptide 6 (17 kDa myosin light chain) (LC17) (Myosin light chain 3) (MLC-3) (Myosin light chain alkali 3) (Myosin light chain A3) (Smooth muscle and nonmuscle myosin light chain alkali 6)
Gene: MYL6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	20308691, 21182205, 21217774
Identification Methods	affinity chromatography technology, cosedimentation through density gradient, phage display
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 151
+	Hs
		368917 ESR1_HUMAN (1-595): 0: 599: 100.00		MYL6B_HUMAN (3-150): 2.63e-42: 141: 81.76
+	Hs
		368863 ESR1_HUMAN (1-595): 0: 599: 100.00		CALM3_HUMAN (5-77): 1.13e-11: 60.6: 28.77
+	Hs
		891574 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		MYL6_HUMAN (1-151): 9.61e-42: 137: 100.00
+	Hs
		487278 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		MYL6_HUMAN (1-151): 9.61e-42: 137: 100.00