HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: LIMA1 (Q9UHB6)
LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm)
Gene: LIMA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33731348
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 759
+	Hs
		1269855 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		369966 ESR1_HUMAN (1-595): 0: 599: 100.00		MILK2_HUMAN (295-569): 1.42e-37: 153: 22.95
+	Hs
		368983 ESR1_HUMAN (1-595): 0: 599: 100.00		CSRP1_HUMAN (254-449): 3.7e-34: 131: 15.82
+	Hs
		150502 ESR1_HUMAN (1-595): 0: 599: 100.00		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		369176 ESR1_HUMAN (1-595): 0: 599: 100.00		PAXI_HUMAN (268-446): 5.9e-14: 77.3: 14.53
+	Hs
		1186078 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		MICA3_HUMAN (271-544): 5.7e-43: 170: 23.93
+	Hs
		597770 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		CSRP1_HUMAN (254-449): 3.7e-34: 131: 15.82
+	Hs
		150608 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		377355 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		CSRP2_HUMAN (254-450): 3.35e-41: 151: 18.27
+	Rn
		415152 GCR_RAT (5-557): 9.7e-106: 338: 22.68		LASP1_RAT (389-572): 1.31e-40: 151: 18.78
+	Hs
		823459 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PAXI_HUMAN (268-446): 5.9e-14: 77.3: 14.53
+	Hs
		200153 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		TGFI1_HUMAN (263-447): 1.47e-16: 85: 15.64
+	Hs
		200156 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		TGFI1_HUMAN (263-447): 1.47e-16: 85: 15.64