HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: CPEB4 (Q17RY0)
Cytoplasmic polyadenylation element-binding protein 4 (CPE-BP4) (CPE-binding protein 4) (hCPEB-4)
Gene: CPEB4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	36244648, 38496616
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0046872 - metal ion binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 729
+	Hs
		374171 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP4_HUMAN (277-728): 9.25e-61: 217: 10.37
+	Hs
		374671 RAF1_HUMAN (1-648): 0: 652: 100.00		MSI2H_HUMAN (459-666): 5.04e-44: 163: 20.19
+	Hs
		373604 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP1_HUMAN (463-673): 1.69e-32: 135: 17.54
+	Hs
		488705 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PABP4_HUMAN (277-728): 9.25e-61: 217: 10.37
+	Hs
		488548 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PABP1_HUMAN (463-673): 1.69e-32: 135: 17.54
+	Hs
		522960 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP4_HUMAN (277-728): 9.25e-61: 217: 10.37
+	Hs
		523106 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		MSI2H_HUMAN (459-666): 5.04e-44: 163: 20.19
+	Hs
		433441 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		MSI2H_HUMAN (459-666): 5.04e-44: 163: 20.19
+	Hs
		516342 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP1_HUMAN (463-673): 1.69e-32: 135: 17.54
+	Hs
		523147 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP3_HUMAN (463-673): 3.42e-30: 128: 17.06